Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EKY02854.1Hypothetical protein. (723 aa)    
Predicted Functional Partners:
EKX97112.1
UvrD/REP helicase; KEGG: pmz:HMPREF0659_A6530 7.0e-208 UvrD/REP helicase K03657; Psort location: Cytoplasmic, score: 9.97.
  
 0.968
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.961
EKX98167.1
Helicase protein; KEGG: lsp:Bsph_0793 3.8e-17 ATP-dependent helicase YqhH; Psort location: Cytoplasmic, score: 8.96.
  
 0.953
EKX99756.1
RecF/RecN/SMC protein; KEGG: fnu:FN0522 7.9e-16 exonuclease SBCC K03546; Psort location: Cytoplasmic, score: 8.96.
  
 0.931
EKY03129.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.925
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.919
EKY03683.1
UvrD/REP helicase; KEGG: pru:PRU_0995 1.3e-261 putative ATP-dependent DNA helicase PcrA; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97.
  
 0.901
EKX98744.1
Tetratricopeptide repeat domain protein; KEGG: dre:326729 6.6e-45 pif1, cb934, fe11d03, wu:fe11d03, zgc:56161; PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae) K01529; Psort location: Cytoplasmic, score: 8.96.
 
 
0.890
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 0.831
EKY02832.1
DNA topoisomerase.
 
 0.817
Your Current Organism:
Prevotella saccharolytica
NCBI taxonomy Id: 1127699
Other names: P. saccharolytica F0055, Prevotella saccharolytica F0055, Prevotella saccharolytica str. F0055, Prevotella saccharolytica strain F0055
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