Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (273 aa)    
Predicted Functional Partners:
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
 0.997
EKY03451.1
KEGG: pru:PRU_0166 4.1e-155 ilvE; branched-chain-amino-acid transaminase K00826; Psort location: Cytoplasmic, score: 9.26.
     
 0.868
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
     
 0.868
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
  
  
 0.864
EKX96041.1
Ketopantoate reductase PanE/ApbA; KEGG: smc:SmuNN2025_1671 6.8e-75 hypothetical protein; K00077 2-dehydropantoate 2-reductase; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.857
EKY02863.1
Transporter, major facilitator family protein.
  
  
 0.757
EKY02865.1
HAD hydrolase, family IA, variant 3.
       0.675
EKY01592.1
Hypothetical protein; KEGG: bcv:Bcav_0716 8.7e-06 pantoate/beta-alanine ligase; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.602
rsmG
16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
       0.544
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.531
Your Current Organism:
Prevotella saccharolytica
NCBI taxonomy Id: 1127699
Other names: P. saccharolytica F0055, Prevotella saccharolytica F0055, Prevotella saccharolytica str. F0055, Prevotella saccharolytica strain F0055
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