| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKX97279.1 | EKX98589.1 | HMPREF9151_02197 | HMPREF9151_01931 | Phosphoserine phosphatase SerB. | KEGG: pmz:HMPREF0659_A6944 0. homoserine dehydrogenase K12524; Psort location: CytoplasmicMembrane, score: 8.46. | 0.947 |
| EKX97279.1 | EKX99509.1 | HMPREF9151_02197 | HMPREF9151_01706 | Phosphoserine phosphatase SerB. | KEGG: pmz:HMPREF0659_A5803 4.0e-141 putative D-lactate dehydrogenase; K03778 D-lactate dehydrogenase; Psort location: Cytoplasmic, score: 9.97; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.631 |
| EKX97279.1 | EKY00793.1 | HMPREF9151_02197 | HMPREF9151_01180 | Phosphoserine phosphatase SerB. | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.838 |
| EKX97279.1 | EKY01219.1 | HMPREF9151_02197 | HMPREF9151_01077 | Phosphoserine phosphatase SerB. | Cysteine synthase A; KEGG: pmz:HMPREF0659_A6111 1.8e-131 cysK; cysteine synthase A K01738; Psort location: Cytoplasmic, score: 9.26; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.774 |
| EKX97279.1 | EKY02328.1 | HMPREF9151_02197 | HMPREF9151_00772 | Phosphoserine phosphatase SerB. | KEGG: pmz:HMPREF0659_A5449 1.4e-81 pssA; CDP-diacylglycerol-serine O-phosphatidyltransferase K00998; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.836 |
| EKX97279.1 | EKY02695.1 | HMPREF9151_02197 | HMPREF9151_00741 | Phosphoserine phosphatase SerB. | KEGG: pmz:HMPREF0659_A5807 2.3e-170 L-serine ammonia-lyase K01752; Psort location: Cytoplasmic, score: 9.26. | 0.884 |
| EKX97279.1 | EKY04270.1 | HMPREF9151_02197 | HMPREF9151_00044 | Phosphoserine phosphatase SerB. | Putative serine O-acetyltransferase; KEGG: bth:BT_3256 8.3e-102 serine acetyltransferase; K00640 serine O-acetyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.878 |
| EKX97279.1 | glyA | HMPREF9151_02197 | HMPREF9151_01568 | Phosphoserine phosphatase SerB. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.949 |
| EKX97279.1 | metAA | HMPREF9151_02197 | HMPREF9151_00454 | Phosphoserine phosphatase SerB. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.829 |
| EKX98589.1 | EKX97279.1 | HMPREF9151_01931 | HMPREF9151_02197 | KEGG: pmz:HMPREF0659_A6944 0. homoserine dehydrogenase K12524; Psort location: CytoplasmicMembrane, score: 8.46. | Phosphoserine phosphatase SerB. | 0.947 |
| EKX98589.1 | EKX99509.1 | HMPREF9151_01931 | HMPREF9151_01706 | KEGG: pmz:HMPREF0659_A6944 0. homoserine dehydrogenase K12524; Psort location: CytoplasmicMembrane, score: 8.46. | KEGG: pmz:HMPREF0659_A5803 4.0e-141 putative D-lactate dehydrogenase; K03778 D-lactate dehydrogenase; Psort location: Cytoplasmic, score: 9.97; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.442 |
| EKX98589.1 | EKY00793.1 | HMPREF9151_01931 | HMPREF9151_01180 | KEGG: pmz:HMPREF0659_A6944 0. homoserine dehydrogenase K12524; Psort location: CytoplasmicMembrane, score: 8.46. | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.584 |
| EKX98589.1 | EKY01219.1 | HMPREF9151_01931 | HMPREF9151_01077 | KEGG: pmz:HMPREF0659_A6944 0. homoserine dehydrogenase K12524; Psort location: CytoplasmicMembrane, score: 8.46. | Cysteine synthase A; KEGG: pmz:HMPREF0659_A6111 1.8e-131 cysK; cysteine synthase A K01738; Psort location: Cytoplasmic, score: 9.26; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.800 |
| EKX98589.1 | EKY02328.1 | HMPREF9151_01931 | HMPREF9151_00772 | KEGG: pmz:HMPREF0659_A6944 0. homoserine dehydrogenase K12524; Psort location: CytoplasmicMembrane, score: 8.46. | KEGG: pmz:HMPREF0659_A5449 1.4e-81 pssA; CDP-diacylglycerol-serine O-phosphatidyltransferase K00998; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.695 |
| EKX98589.1 | EKY02695.1 | HMPREF9151_01931 | HMPREF9151_00741 | KEGG: pmz:HMPREF0659_A6944 0. homoserine dehydrogenase K12524; Psort location: CytoplasmicMembrane, score: 8.46. | KEGG: pmz:HMPREF0659_A5807 2.3e-170 L-serine ammonia-lyase K01752; Psort location: Cytoplasmic, score: 9.26. | 0.855 |
| EKX98589.1 | EKY04270.1 | HMPREF9151_01931 | HMPREF9151_00044 | KEGG: pmz:HMPREF0659_A6944 0. homoserine dehydrogenase K12524; Psort location: CytoplasmicMembrane, score: 8.46. | Putative serine O-acetyltransferase; KEGG: bth:BT_3256 8.3e-102 serine acetyltransferase; K00640 serine O-acetyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.884 |
| EKX98589.1 | glyA | HMPREF9151_01931 | HMPREF9151_01568 | KEGG: pmz:HMPREF0659_A6944 0. homoserine dehydrogenase K12524; Psort location: CytoplasmicMembrane, score: 8.46. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.824 |
| EKX98589.1 | metAA | HMPREF9151_01931 | HMPREF9151_00454 | KEGG: pmz:HMPREF0659_A6944 0. homoserine dehydrogenase K12524; Psort location: CytoplasmicMembrane, score: 8.46. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.939 |
| EKX99509.1 | EKX97279.1 | HMPREF9151_01706 | HMPREF9151_02197 | KEGG: pmz:HMPREF0659_A5803 4.0e-141 putative D-lactate dehydrogenase; K03778 D-lactate dehydrogenase; Psort location: Cytoplasmic, score: 9.97; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Phosphoserine phosphatase SerB. | 0.631 |
| EKX99509.1 | EKX98589.1 | HMPREF9151_01706 | HMPREF9151_01931 | KEGG: pmz:HMPREF0659_A5803 4.0e-141 putative D-lactate dehydrogenase; K03778 D-lactate dehydrogenase; Psort location: Cytoplasmic, score: 9.97; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | KEGG: pmz:HMPREF0659_A6944 0. homoserine dehydrogenase K12524; Psort location: CytoplasmicMembrane, score: 8.46. | 0.442 |