Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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co-expression
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[Homology]
Score
pfpDiphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (546 aa)    
Predicted Functional Partners:
pgi
KEGG: pru:PRU_1785 8.1e-198 pgi; glucose-6-phosphate isomerase K01810; Psort location: Cytoplasmic, score: 9.97; Belongs to the GPI family.
  
 0.931
EKY01124.1
KEGG: pmz:HMPREF0659_A5379 6.4e-150 fba; fructose-1,6-bisphosphate aldolase, class II K01624; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.870
EKX97503.1
Transketolase, thiamine diphosphate binding domain protein; KEGG: pmz:HMPREF0659_A6472 4.5e-284 putative transketolase; K00615 transketolase; Psort location: Cytoplasmic, score: 9.26; Belongs to the transketolase family.
  
 0.862
EKX96715.1
Kinase, PfkB family; KEGG: pmz:HMPREF0659_A5128 3.8e-113 kinase, PfkB family; K00847 fructokinase; Psort location: Cytoplasmic, score: 8.96.
   
 0.846
EKX98576.1
KEGG: pru:PRU_2880 2.1e-112 manA; mannose-6-phosphate isomerase, class I K01809; Psort location: Cytoplasmic, score: 8.96.
     
 0.840
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
     
  0.829
EKY03608.1
KEGG: bvu:BVU_3516 1.6e-160 fructose-bisphosphate aldolase K01623; Psort location: Cytoplasmic, score: 8.96.
    
 0.763
EKX98504.1
Pyruvate kinase; KEGG: pmz:HMPREF0659_A6470 1.5e-189 pyk; pyruvate kinase K00873; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.763
EKY03104.1
Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: bvu:BVU_3585 2.1e-158 glyceraldehyde 3-phosphate dehydrogenase; K00134 glyceraldehyde 3-phosphate dehydrogenase; Psort location: Cytoplasmic, score: 9.97; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
  
 0.579
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
  
 0.570
Your Current Organism:
Prevotella saccharolytica
NCBI taxonomy Id: 1127699
Other names: P. saccharolytica F0055, Prevotella saccharolytica F0055, Prevotella saccharolytica str. F0055, Prevotella saccharolytica strain F0055
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