prfC protein (Prevotella saccharolytica) - STRING interaction network

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prfC

Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (521 aa)

Predicted Functional Partners:

rpmA

0.789

rpmG

0.758

rplS

0.748

rplT

0.745

rplL

0.737

EKY02359.1

0.726

rpmF

0.718

rplQ

0.717

rplI

0.716

rplM

0.712

Your Current Organism:

Prevotella saccharolytica

NCBI taxonomy Id: 1127699
Other names: P. saccharolytica F0055, Prevotella saccharolytica F0055, Prevotella saccharolytica str. F0055, Prevotella saccharolytica strain F0055

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EKY02359.1	prfC	HMPREF9151_00803	HMPREF9151_00801	Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.	Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	0.726
prfC	EKY02359.1	HMPREF9151_00801	HMPREF9151_00803	Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.	0.726
prfC	rplI	HMPREF9151_00801	HMPREF9151_00728	Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	Ribosomal protein L9; Binds to the 23S rRNA.	0.716
prfC	rplL	HMPREF9151_00801	HMPREF9151_01460	Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.	0.737
prfC	rplM	HMPREF9151_00801	HMPREF9151_00914	Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.712
prfC	rplQ	HMPREF9151_00801	HMPREF9151_02129	Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	Ribosomal protein L17; KEGG: apb:SAR116_2416 6.8e-20 ribosomal protein L17 K02879; Psort location: Cytoplasmic, score: 9.97.	0.717
prfC	rplS	HMPREF9151_00801	HMPREF9151_01109	Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.748
prfC	rplT	HMPREF9151_00801	HMPREF9151_01741	Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.745
prfC	rpmA	HMPREF9151_00801	HMPREF9151_00617	Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	Ribosomal protein L27; KEGG: apb:SAR116_1855 4.3e-25 ribosomal protein L27 K02899; Psort location: Cytoplasmic, score: 9.26; Belongs to the bacterial ribosomal protein bL27 family.	0.789
prfC	rpmF	HMPREF9151_00801	HMPREF9151_01813	Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	Ribosomal protein L32; Psort location: Cytoplasmic, score: 9.26; Belongs to the bacterial ribosomal protein bL32 family.	0.718
prfC	rpmG	HMPREF9151_00801	HMPREF9151_01774	Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	Ribosomal protein L33; KEGG: apb:SAR116_0619 0.0037 ribosomal protein L33 K02913; Belongs to the bacterial ribosomal protein bL33 family.	0.758
rplI	prfC	HMPREF9151_00728	HMPREF9151_00801	Ribosomal protein L9; Binds to the 23S rRNA.	Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	0.716
rplI	rplL	HMPREF9151_00728	HMPREF9151_01460	Ribosomal protein L9; Binds to the 23S rRNA.	Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.	0.990
rplI	rplM	HMPREF9151_00728	HMPREF9151_00914	Ribosomal protein L9; Binds to the 23S rRNA.	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.991
rplI	rplQ	HMPREF9151_00728	HMPREF9151_02129	Ribosomal protein L9; Binds to the 23S rRNA.	Ribosomal protein L17; KEGG: apb:SAR116_2416 6.8e-20 ribosomal protein L17 K02879; Psort location: Cytoplasmic, score: 9.97.	0.992
rplI	rplS	HMPREF9151_00728	HMPREF9151_01109	Ribosomal protein L9; Binds to the 23S rRNA.	Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.992
rplI	rplT	HMPREF9151_00728	HMPREF9151_01741	Ribosomal protein L9; Binds to the 23S rRNA.	Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.992
rplI	rpmA	HMPREF9151_00728	HMPREF9151_00617	Ribosomal protein L9; Binds to the 23S rRNA.	Ribosomal protein L27; KEGG: apb:SAR116_1855 4.3e-25 ribosomal protein L27 K02899; Psort location: Cytoplasmic, score: 9.26; Belongs to the bacterial ribosomal protein bL27 family.	0.987
rplI	rpmF	HMPREF9151_00728	HMPREF9151_01813	Ribosomal protein L9; Binds to the 23S rRNA.	Ribosomal protein L32; Psort location: Cytoplasmic, score: 9.26; Belongs to the bacterial ribosomal protein bL32 family.	0.973
rplI	rpmG	HMPREF9151_00728	HMPREF9151_01774	Ribosomal protein L9; Binds to the 23S rRNA.	Ribosomal protein L33; KEGG: apb:SAR116_0619 0.0037 ribosomal protein L33 K02913; Belongs to the bacterial ribosomal protein bL33 family.	0.980

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