| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKX96670.1 | EKX99504.1 | HMPREF9151_02404 | HMPREF9151_01701 | ABC transporter, ATP-binding protein; KEGG: pmz:HMPREF0659_A6183 1.9e-109 lptB; lipopolysaccharide ABC transporter, ATP-binding protein LptB K06861; Psort location: Cytoplasmic, score: 9.12. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.634 |
| EKX96670.1 | EKY01574.1 | HMPREF9151_02404 | HMPREF9151_00998 | ABC transporter, ATP-binding protein; KEGG: pmz:HMPREF0659_A6183 1.9e-109 lptB; lipopolysaccharide ABC transporter, ATP-binding protein LptB K06861; Psort location: Cytoplasmic, score: 9.12. | acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.698 |
| EKX96670.1 | EKY03140.1 | HMPREF9151_02404 | HMPREF9151_00485 | ABC transporter, ATP-binding protein; KEGG: pmz:HMPREF0659_A6183 1.9e-109 lptB; lipopolysaccharide ABC transporter, ATP-binding protein LptB K06861; Psort location: Cytoplasmic, score: 9.12. | KEGG: pmz:HMPREF0659_A5655 5.3e-139 putative arabinose 5-phosphate isomerase; K06041 arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.571 |
| EKX96670.1 | lpxC | HMPREF9151_02404 | HMPREF9151_00999 | ABC transporter, ATP-binding protein; KEGG: pmz:HMPREF0659_A6183 1.9e-109 lptB; lipopolysaccharide ABC transporter, ATP-binding protein LptB K06861; Psort location: Cytoplasmic, score: 9.12. | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. | 0.615 |
| EKX96670.1 | lpxD | HMPREF9151_02404 | HMPREF9151_01000 | ABC transporter, ATP-binding protein; KEGG: pmz:HMPREF0659_A6183 1.9e-109 lptB; lipopolysaccharide ABC transporter, ATP-binding protein LptB K06861; Psort location: Cytoplasmic, score: 9.12. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.711 |
| EKX96670.1 | lpxK | HMPREF9151_02404 | HMPREF9151_00536 | ABC transporter, ATP-binding protein; KEGG: pmz:HMPREF0659_A6183 1.9e-109 lptB; lipopolysaccharide ABC transporter, ATP-binding protein LptB K06861; Psort location: Cytoplasmic, score: 9.12. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.471 |
| EKX99504.1 | EKX96670.1 | HMPREF9151_01701 | HMPREF9151_02404 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | ABC transporter, ATP-binding protein; KEGG: pmz:HMPREF0659_A6183 1.9e-109 lptB; lipopolysaccharide ABC transporter, ATP-binding protein LptB K06861; Psort location: Cytoplasmic, score: 9.12. | 0.634 |
| EKX99504.1 | EKY01574.1 | HMPREF9151_01701 | HMPREF9151_00998 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.945 |
| EKX99504.1 | EKY03140.1 | HMPREF9151_01701 | HMPREF9151_00485 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | KEGG: pmz:HMPREF0659_A5655 5.3e-139 putative arabinose 5-phosphate isomerase; K06041 arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.701 |
| EKX99504.1 | kdsB | HMPREF9151_01701 | HMPREF9151_00677 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.758 |
| EKX99504.1 | lpxC | HMPREF9151_01701 | HMPREF9151_00999 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. | 0.811 |
| EKX99504.1 | lpxD | HMPREF9151_01701 | HMPREF9151_01000 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.976 |
| EKX99504.1 | lpxK | HMPREF9151_01701 | HMPREF9151_00536 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.971 |
| EKY01573.1 | EKY01574.1 | HMPREF9151_00997 | HMPREF9151_00998 | KEGG: pmz:HMPREF0659_A5505 4.3e-121 UDP-N-acetylglucosamine 2-epimerase K01791; Psort location: Cytoplasmic, score: 9.97. | acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.953 |
| EKY01573.1 | EKY01577.1 | HMPREF9151_00997 | HMPREF9151_01001 | KEGG: pmz:HMPREF0659_A5505 4.3e-121 UDP-N-acetylglucosamine 2-epimerase K01791; Psort location: Cytoplasmic, score: 9.97. | HD domain protein; KEGG: fba:FIC_01915 1.3e-85 deoxyguanosinetriphosphate triphosphohydrolase K06885; Psort location: Cytoplasmic, score: 8.96. | 0.563 |
| EKY01573.1 | lpxC | HMPREF9151_00997 | HMPREF9151_00999 | KEGG: pmz:HMPREF0659_A5505 4.3e-121 UDP-N-acetylglucosamine 2-epimerase K01791; Psort location: Cytoplasmic, score: 9.97. | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. | 0.689 |
| EKY01573.1 | lpxD | HMPREF9151_00997 | HMPREF9151_01000 | KEGG: pmz:HMPREF0659_A5505 4.3e-121 UDP-N-acetylglucosamine 2-epimerase K01791; Psort location: Cytoplasmic, score: 9.97. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.810 |
| EKY01573.1 | murA | HMPREF9151_00997 | HMPREF9151_01297 | KEGG: pmz:HMPREF0659_A5505 4.3e-121 UDP-N-acetylglucosamine 2-epimerase K01791; Psort location: Cytoplasmic, score: 9.97. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.845 |
| EKY01574.1 | EKX96670.1 | HMPREF9151_00998 | HMPREF9151_02404 | acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | ABC transporter, ATP-binding protein; KEGG: pmz:HMPREF0659_A6183 1.9e-109 lptB; lipopolysaccharide ABC transporter, ATP-binding protein LptB K06861; Psort location: Cytoplasmic, score: 9.12. | 0.698 |
| EKY01574.1 | EKX99504.1 | HMPREF9151_00998 | HMPREF9151_01701 | acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.945 |