STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EKY01476.1Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (192 aa)    
Predicted Functional Partners:
cmk
Cytidylate kinase; KEGG: pru:PRU_1828 2.6e-91 cmk; cytidylate kinase K00945; Psort location: Cytoplasmic, score: 9.97.
    
  0.842
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
    
  0.841
EKY03917.1
KEGG: pru:PRU_2851 0. nrdD_2; anaerobic ribonucleoside-triphosphate reductase K00527; Psort location: Cytoplasmic, score: 9.97.
     
  0.829
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
     
  0.829
udk
Uridine kinase; KEGG: pmz:HMPREF0659_A7128 1.2e-91 udk; uridine kinase K00876; Psort location: Cytoplasmic, score: 9.97.
     
  0.829
pyrF
KEGG: pmz:HMPREF0659_A6727 4.6e-108 pyrF; orotidine 5'-phosphate decarboxylase K01591; Belongs to the OMP decarboxylase family. Type 2 subfamily.
     
  0.829
tdk
Thymidine kinase; KEGG: pmz:HMPREF0659_A5428 5.4e-82 tdk; thymidine kinase K00857; Psort location: Cytoplasmic, score: 9.97.
     
  0.829
surE
5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.829
pyrH
UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
     
  0.829
EKX98446.1
KEGG: pmz:HMPREF0659_A6372 1.0e-96 putative uracil phosphoribosyltransferase; K00761 uracil phosphoribosyltransferase; Psort location: Cytoplasmic, score: 9.97.
     
  0.829
Your Current Organism:
Prevotella saccharolytica
NCBI taxonomy Id: 1127699
Other names: P. saccharolytica F0055, Prevotella saccharolytica F0055, Prevotella saccharolytica str. F0055, Prevotella saccharolytica strain F0055
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