| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKX96743.1 | EKX97289.1 | HMPREF9151_02369 | HMPREF9151_02207 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | Ser/Thr phosphatase family protein. | 0.829 |
| EKX96743.1 | EKX99289.1 | HMPREF9151_02369 | HMPREF9151_01772 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.8e-16 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | 0.920 |
| EKX96743.1 | EKX99645.1 | HMPREF9151_02369 | HMPREF9151_01591 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | NAD(+) diphosphatase family protein; KEGG: pmz:HMPREF0659_A5588 2.6e-89 hydrolase, NUDIX family; K03426 NAD+ diphosphatase; Psort location: Cytoplasmic, score: 8.96. | 0.832 |
| EKX96743.1 | EKY03618.1 | HMPREF9151_02369 | HMPREF9151_00260 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | Putative NAD-dependent deacetylase; KEGG: pmz:HMPREF0659_A5082 2.4e-79 transcriptional regulator, Sir2 family; K12410 NAD-dependent deacetylase; Psort location: Cytoplasmic, score: 9.26. | 0.539 |
| EKX96743.1 | nadD | HMPREF9151_02369 | HMPREF9151_01291 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.937 |
| EKX96743.1 | nadE | HMPREF9151_02369 | HMPREF9151_00396 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.749 |
| EKX96743.1 | surE | HMPREF9151_02369 | HMPREF9151_01700 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.829 |
| EKX97289.1 | EKX96743.1 | HMPREF9151_02207 | HMPREF9151_02369 | Ser/Thr phosphatase family protein. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.829 |
| EKX97289.1 | EKX99289.1 | HMPREF9151_02207 | HMPREF9151_01772 | Ser/Thr phosphatase family protein. | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.8e-16 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | 0.839 |
| EKX97289.1 | EKX99645.1 | HMPREF9151_02207 | HMPREF9151_01591 | Ser/Thr phosphatase family protein. | NAD(+) diphosphatase family protein; KEGG: pmz:HMPREF0659_A5588 2.6e-89 hydrolase, NUDIX family; K03426 NAD+ diphosphatase; Psort location: Cytoplasmic, score: 8.96. | 0.837 |
| EKX97289.1 | gmk | HMPREF9151_02207 | HMPREF9151_01292 | Ser/Thr phosphatase family protein. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.829 |
| EKX97289.1 | nadD | HMPREF9151_02207 | HMPREF9151_01291 | Ser/Thr phosphatase family protein. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.839 |
| EKX97289.1 | surE | HMPREF9151_02207 | HMPREF9151_01700 | Ser/Thr phosphatase family protein. | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.839 |
| EKX99289.1 | EKX96743.1 | HMPREF9151_01772 | HMPREF9151_02369 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.8e-16 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.920 |
| EKX99289.1 | EKX97289.1 | HMPREF9151_01772 | HMPREF9151_02207 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.8e-16 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | Ser/Thr phosphatase family protein. | 0.839 |
| EKX99289.1 | EKX99645.1 | HMPREF9151_01772 | HMPREF9151_01591 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.8e-16 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | NAD(+) diphosphatase family protein; KEGG: pmz:HMPREF0659_A5588 2.6e-89 hydrolase, NUDIX family; K03426 NAD+ diphosphatase; Psort location: Cytoplasmic, score: 8.96. | 0.848 |
| EKX99289.1 | EKY03618.1 | HMPREF9151_01772 | HMPREF9151_00260 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.8e-16 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | Putative NAD-dependent deacetylase; KEGG: pmz:HMPREF0659_A5082 2.4e-79 transcriptional regulator, Sir2 family; K12410 NAD-dependent deacetylase; Psort location: Cytoplasmic, score: 9.26. | 0.551 |
| EKX99289.1 | nadD | HMPREF9151_01772 | HMPREF9151_01291 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.8e-16 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.929 |
| EKX99289.1 | nadE | HMPREF9151_01772 | HMPREF9151_00396 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.8e-16 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.910 |
| EKX99289.1 | nadK | HMPREF9151_01772 | HMPREF9151_01986 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.8e-16 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.521 |