Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EKX99650.1KEGG: pmz:HMPREF0659_A5999 2.1e-151 amidohydrolase family protein; K01465 dihydroorotase; Psort location: Cytoplasmic, score: 9.97. (441 aa)    
Predicted Functional Partners:
pyrB
KEGG: pru:PRU_0637 4.7e-147 pyrB; aspartate carbamoyltransferase K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 0.999
carA
KEGG: pmz:HMPREF0659_A5880 6.0e-170 carA; carbamoyl-phosphate synthase, small subunit K01956; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarA family.
  
 0.993
pyrD
Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate.
 
 0.990
EKX98774.1
KEGG: pmz:HMPREF0659_A5879 0. carB; carbamoyl-phosphate synthase, large subunit K01955; Psort location: Cytoplasmic, score: 9.97.
 
 0.988
pyrK
Putative dihydroorotate oxidase, electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
 
 
 0.968
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
 
 0.956
pyrF
KEGG: pmz:HMPREF0659_A6727 4.6e-108 pyrF; orotidine 5'-phosphate decarboxylase K01591; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
  
 0.930
pyrI
Aspartate carbamoyltransferase regulatory chain, allosteric domain protein; Involved in allosteric regulation of aspartate carbamoyltransferase.
    
 0.854
EKX99649.1
Hypothetical protein.
       0.825
EKX99651.1
Vitamin B12 dependent methionine synthase, activation domain protein; KEGG: pdi:BDI_0415 7.1e-53 putative 5-methyltetrahydrofolate--homocysteine methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.97.
       0.659
Your Current Organism:
Prevotella saccharolytica
NCBI taxonomy Id: 1127699
Other names: P. saccharolytica F0055, Prevotella saccharolytica F0055, Prevotella saccharolytica str. F0055, Prevotella saccharolytica strain F0055
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