STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EKX99483.1KEGG: pmz:HMPREF0659_A6393 2.0e-114 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; K02517 lipid A biosynthesis lauroyl acyltransferase; Psort location: Cytoplasmic, score: 8.96. (323 aa)    
Predicted Functional Partners:
EKY00024.1
3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
  
 0.931
EKX99484.1
Arylsulfatase; KEGG: fps:FP0883 4.8e-129 phosphoglycerol transferase; Psort location: CytoplasmicMembrane, score: 10.00.
       0.825
EKX99486.1
KEGG: pru:PRU_2913 1.3e-263 msbA; lipid A export permease/ATP-binding protein; K11085 ATP-binding cassette, subfamily B, bacterial MsbA; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.811
EKX99482.1
Hypothetical protein.
       0.787
EKX99504.1
lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.725
lpxD
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
 
   
 0.681
lpxC
Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily.
 
   
 0.680
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
 
 0.663
EKY00560.1
Heptosyltransferase.
 
  
 0.591
EKX99481.1
Hypothetical protein; KEGG: bce:BC0314 8.3e-23 glycosyltransferase; Psort location: Cytoplasmic, score: 8.96.
       0.578
Your Current Organism:
Prevotella saccharolytica
NCBI taxonomy Id: 1127699
Other names: P. saccharolytica F0055, Prevotella saccharolytica F0055, Prevotella saccharolytica str. F0055, Prevotella saccharolytica strain F0055
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.