Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EKX99537.1KEGG: pmz:HMPREF0659_A5975 1.3e-117 holA; DNA polymerase III, delta subunit K02340; Psort location: Cytoplasmic, score: 8.96. (342 aa)    
Predicted Functional Partners:
EKY03129.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.990
EKY02326.1
KEGG: pru:PRU_1896 0. dnaE; DNA polymerase III subunit alpha K02337; Psort location: Cytoplasmic, score: 9.97.
   
 0.981
dnaX
DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
 
 0.975
EKX96217.1
Putative DNA polymerase III, delta' subunit; KEGG: pmz:HMPREF0659_A5422 9.6e-124 hypothetical protein; K02341 DNA polymerase III subunit delta'; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.975
EKY03130.1
Exonuclease; KEGG: pmz:HMPREF0659_A5674 1.5e-109 exonuclease; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 8.96.
    
 0.896
EKX97336.1
KEGG: pru:PRU_2813 7.2e-71 exonuclease; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.26.
    
 0.896
EKX99536.1
KEGG: abu:Abu_1717 0.00065 hsdM; type I restriction-modification system, M subunit, putative.
 
     0.809
EKX97112.1
UvrD/REP helicase; KEGG: pmz:HMPREF0659_A6530 7.0e-208 UvrD/REP helicase K03657; Psort location: Cytoplasmic, score: 9.97.
   
 0.685
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.554
EKX99534.1
DnaJ domain protein; KEGG: tgo:TGME49_017710 0.00023 DnaJ domain-containing protein; Psort location: CytoplasmicMembrane, score: 7.88.
     
 0.526
Your Current Organism:
Prevotella saccharolytica
NCBI taxonomy Id: 1127699
Other names: P. saccharolytica F0055, Prevotella saccharolytica F0055, Prevotella saccharolytica str. F0055, Prevotella saccharolytica strain F0055
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