| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKX97505.1 | tsaD | HMPREF9151_02103 | HMPREF9151_01771 | Sua5/YciO/YrdC/YwlC family protein; KEGG: dpo:Dpse_GA17233 4.8e-15 GA17233 gene product from transcript GA17233-RA; K03019 DNA-directed RNA polymerase III subunit C11; Psort location: Cytoplasmic, score: 8.96; Belongs to the SUA5 family. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.676 |
| EKX99286.1 | EKX99289.1 | HMPREF9151_01769 | HMPREF9151_01772 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.8e-16 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | 0.575 |
| EKX99286.1 | map | HMPREF9151_01769 | HMPREF9151_01770 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 0.551 |
| EKX99286.1 | tsaD | HMPREF9151_01769 | HMPREF9151_01771 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.546 |
| EKX99289.1 | EKX99286.1 | HMPREF9151_01772 | HMPREF9151_01769 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.8e-16 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.575 |
| EKX99289.1 | EKX99292.1 | HMPREF9151_01772 | HMPREF9151_01775 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.8e-16 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | Hypothetical protein. | 0.644 |
| EKX99289.1 | map | HMPREF9151_01772 | HMPREF9151_01770 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.8e-16 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 0.762 |
| EKX99289.1 | rpmB | HMPREF9151_01772 | HMPREF9151_01773 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.8e-16 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | Ribosomal protein L28; KEGG: apb:SAR116_1905 1.3e-07 LSU ribosomal protein L28P K02902; Psort location: Cytoplasmic, score: 9.26; Belongs to the bacterial ribosomal protein bL28 family. | 0.655 |
| EKX99289.1 | rpmG | HMPREF9151_01772 | HMPREF9151_01774 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.8e-16 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | Ribosomal protein L33; KEGG: apb:SAR116_0619 0.0037 ribosomal protein L33 K02913; Belongs to the bacterial ribosomal protein bL33 family. | 0.655 |
| EKX99289.1 | tsaD | HMPREF9151_01772 | HMPREF9151_01771 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.8e-16 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.773 |
| EKX99292.1 | EKX99289.1 | HMPREF9151_01775 | HMPREF9151_01772 | Hypothetical protein. | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.8e-16 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | 0.644 |
| EKX99292.1 | map | HMPREF9151_01775 | HMPREF9151_01770 | Hypothetical protein. | Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 0.594 |
| EKX99292.1 | rpmB | HMPREF9151_01775 | HMPREF9151_01773 | Hypothetical protein. | Ribosomal protein L28; KEGG: apb:SAR116_1905 1.3e-07 LSU ribosomal protein L28P K02902; Psort location: Cytoplasmic, score: 9.26; Belongs to the bacterial ribosomal protein bL28 family. | 0.934 |
| EKX99292.1 | rpmG | HMPREF9151_01775 | HMPREF9151_01774 | Hypothetical protein. | Ribosomal protein L33; KEGG: apb:SAR116_0619 0.0037 ribosomal protein L33 K02913; Belongs to the bacterial ribosomal protein bL33 family. | 0.934 |
| EKX99292.1 | tsaD | HMPREF9151_01775 | HMPREF9151_01771 | Hypothetical protein. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.595 |
| EKY00510.1 | EKY03261.1 | HMPREF9151_01294 | HMPREF9151_00417 | Universal bacterial protein YeaZ; KEGG: gfo:GFO_0202 4.0e-38 M22 family peptidase K01417; Psort location: Cytoplasmic, score: 8.96. | Hydrolase, P-loop family; KEGG: cms:CMS_0521 8.3e-08 alr*; putative alanine racemase fusion protein K01775; Psort location: Cytoplasmic, score: 9.97. | 0.955 |
| EKY00510.1 | tsaD | HMPREF9151_01294 | HMPREF9151_01771 | Universal bacterial protein YeaZ; KEGG: gfo:GFO_0202 4.0e-38 M22 family peptidase K01417; Psort location: Cytoplasmic, score: 8.96. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.930 |
| EKY03261.1 | EKY00510.1 | HMPREF9151_00417 | HMPREF9151_01294 | Hydrolase, P-loop family; KEGG: cms:CMS_0521 8.3e-08 alr*; putative alanine racemase fusion protein K01775; Psort location: Cytoplasmic, score: 9.97. | Universal bacterial protein YeaZ; KEGG: gfo:GFO_0202 4.0e-38 M22 family peptidase K01417; Psort location: Cytoplasmic, score: 8.96. | 0.955 |
| EKY03261.1 | tsaD | HMPREF9151_00417 | HMPREF9151_01771 | Hydrolase, P-loop family; KEGG: cms:CMS_0521 8.3e-08 alr*; putative alanine racemase fusion protein K01775; Psort location: Cytoplasmic, score: 9.97. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.874 |
| lolD | tsaD | HMPREF9151_02209 | HMPREF9151_01771 | Lipoprotein releasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.639 |