Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EKX99114.1RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (738 aa)    
Predicted Functional Partners:
EKY03884.1
Pyruvate synthase; KEGG: pmz:HMPREF0659_A5561 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 8.96.
  
  0.928
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.855
EKX99498.1
Putative GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
  
 
0.854
ribBA
3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
 0.847
EKX98133.1
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
   
 
  0.830
EKY03917.1
KEGG: pru:PRU_2851 0. nrdD_2; anaerobic ribonucleoside-triphosphate reductase K00527; Psort location: Cytoplasmic, score: 9.97.
     
  0.829
EKY03550.1
Adenylate cyclase; KEGG: pru:PRU_2493 5.3e-52 adenylate cyclase; Psort location: Cytoplasmic, score: 8.96.
     
  0.829
folE
GTP cyclohydrolase I; KEGG: pru:PRU_1862 2.9e-83 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 9.97.
     
  0.829
rplV
Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
  
 
   0.812
rpsF
Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
  
 
   0.784
Your Current Organism:
Prevotella saccharolytica
NCBI taxonomy Id: 1127699
Other names: P. saccharolytica F0055, Prevotella saccharolytica F0055, Prevotella saccharolytica str. F0055, Prevotella saccharolytica strain F0055
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