Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EKX98784.1Cys/Met metabolism PLP-dependent enzyme; KEGG: pmz:HMPREF0659_A5993 1.7e-158 putative O-acetylhomoserine aminocarboxypropyltransferase; K01740 O-acetylhomoserine (thiol)-lyase; Psort location: Cytoplasmic, score: 9.97. (391 aa)    
Predicted Functional Partners:
EKX98783.1
KEGG: pmz:HMPREF0659_A5992 1.2e-166 putative cystathionine beta-lyase PatB; K14155 cystathione beta-lyase; Psort location: Cytoplasmic, score: 9.97.
   
 0.958
metAA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
 
 
 0.925
EKX99286.1
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.904
EKY01219.1
Cysteine synthase A; KEGG: pmz:HMPREF0659_A6111 1.8e-131 cysK; cysteine synthase A K01738; Psort location: Cytoplasmic, score: 9.26; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 
 0.903
EKX98589.1
KEGG: pmz:HMPREF0659_A6944 0. homoserine dehydrogenase K12524; Psort location: CytoplasmicMembrane, score: 8.46.
  
 
 0.894
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
 
 0.853
luxS
S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
     
  0.829
EKX99507.1
GAF domain protein; KEGG: sti:Sthe_3242 0.00045 GAF sensor signal transduction histidine kinase.
     
  0.829
EKX99651.1
Vitamin B12 dependent methionine synthase, activation domain protein; KEGG: pdi:BDI_0415 7.1e-53 putative 5-methyltetrahydrofolate--homocysteine methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.802
EKX98785.1
Hypothetical protein; Psort location: OuterMembrane, score: 9.49.
       0.737
Your Current Organism:
Prevotella saccharolytica
NCBI taxonomy Id: 1127699
Other names: P. saccharolytica F0055, Prevotella saccharolytica F0055, Prevotella saccharolytica str. F0055, Prevotella saccharolytica strain F0055
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