Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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mutLDNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (609 aa)    
Predicted Functional Partners:
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
 0.985
EKY01030.1
MutS domain V protein; KEGG: btk:BT9727_3510 2.3e-13 mutS; DNA mismatch repair protein MutS K03555; Psort location: CytoplasmicMembrane, score: 9.99.
 
 0.974
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.957
EKY03129.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.956
EKX97112.1
UvrD/REP helicase; KEGG: pmz:HMPREF0659_A6530 7.0e-208 UvrD/REP helicase K03657; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.768
EKY02854.1
Hypothetical protein.
   
 0.766
EKX96911.1
KEGG: pmz:HMPREF0659_A6179 3.6e-298 recQ; ATP-dependent DNA helicase RecQ K03654; Psort location: Cytoplasmic, score: 9.97.
  
 0.727
EKY03683.1
UvrD/REP helicase; KEGG: pru:PRU_0995 1.3e-261 putative ATP-dependent DNA helicase PcrA; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.698
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 
 0.685
EKX99321.1
KEGG: pru:PRU_0554 1.6e-215 RecQ family ATP-dependent DNA helicase; K03654 ATP-dependent DNA helicase RecQ; Psort location: Cytoplasmic, score: 9.97.
  
 0.667
Your Current Organism:
Prevotella saccharolytica
NCBI taxonomy Id: 1127699
Other names: P. saccharolytica F0055, Prevotella saccharolytica F0055, Prevotella saccharolytica str. F0055, Prevotella saccharolytica strain F0055
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