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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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prsRibose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (312 aa)    
Predicted Functional Partners:
EKX97503.1
Transketolase, thiamine diphosphate binding domain protein; KEGG: pmz:HMPREF0659_A6472 4.5e-284 putative transketolase; K00615 transketolase; Psort location: Cytoplasmic, score: 9.26; Belongs to the transketolase family.
   
 
 0.907
EKX98776.1
KEGG: pmz:HMPREF0659_A5881 1.2e-251 class II glutamine amidotransferase; K00764 amidophosphoribosyltransferase; Psort location: Cytoplasmic, score: 8.96.
  
 0.877
EKX97504.1
KEGG: pru:PRU_0392 1.3e-57 rpiB; ribose-5-phosphate isomerase B K01808; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.875
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.873
EKX99490.1
KEGG: bfr:BF1478 8.6e-242 phosphoglucomutase phosphomannomutase; K01840 phosphomannomutase; Psort location: Cytoplasmic, score: 8.96.
  
 0.855
EKY02005.1
Hydrolase, NUDIX family; KEGG: bfr:BF4292 6.5e-54 putative NUDIX/MutT family protein; K01515 ADP-ribose pyrophosphatase; Psort location: Cytoplasmic, score: 8.96.
    
 0.838
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
  
 
 0.834
pdxS
Pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
   
 
  0.830
pdxT
Pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
     
  0.829
clpP
Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
 0.772
Your Current Organism:
Prevotella saccharolytica
NCBI taxonomy Id: 1127699
Other names: P. saccharolytica F0055, Prevotella saccharolytica F0055, Prevotella saccharolytica str. F0055, Prevotella saccharolytica strain F0055
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