STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sucDsuccinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (310 aa)    
Predicted Functional Partners:
sucC
succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.999
EKX99633.1
Respiratory-chain NADH dehydrogenase, subunit.
  
 
 0.981
EKY03884.1
Pyruvate synthase; KEGG: pmz:HMPREF0659_A5561 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 8.96.
  
 0.979
EKX96357.1
KEGG: pmz:HMPREF0659_A5049 9.4e-117 succinate dehydrogenase/fumarate reductase iron-sulfur subunit K00240; Psort location: Cytoplasmic, score: 8.96.
  
 0.974
EKX96355.1
KEGG: pmz:HMPREF0659_A5048 0. sdhA; succinate dehydrogenase flavoprotein subunit K00239; Psort location: CytoplasmicMembrane, score: 7.88.
  
 0.967
EKX97521.1
KEGG: pmz:HMPREF0659_A6381 1.2e-267 2-oxoacid:acceptor oxidoreductase, alpha subunit; K00174 2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Psort location: Cytoplasmic, score: 8.96.
    
 0.892
EKY02824.1
Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.880
EKX96211.1
KEGG: pru:PRU_2260 6.9e-137 pta; phosphate acetyltransferase K00625; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.858
EKY00506.1
AMP-binding enzyme; KEGG: pru:PRU_2205 2.1e-238 AMP-binding enzyme; K01895 acetyl-CoA synthetase; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.850
EKX96354.1
KEGG: pmz:HMPREF0659_A5047 1.2e-100 succinate dehydrogenase cytochrome b subunit, b558 family; K00241 succinate dehydrogenase cytochrome b-556 subunit; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.848
Your Current Organism:
Prevotella saccharolytica
NCBI taxonomy Id: 1127699
Other names: P. saccharolytica F0055, Prevotella saccharolytica F0055, Prevotella saccharolytica str. F0055, Prevotella saccharolytica strain F0055
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