Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EKX97275.1Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (453 aa)    
Predicted Functional Partners:
EKY03095.1
Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
    
 0.549
EKY00546.1
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
 
 0.527
EKX96749.1
comF family protein; KEGG: chu:CHU_3495 6.6e-22 purF; amidophosphoribosyltransferase K00764; Psort location: Cytoplasmic, score: 9.97.
  
    0.523
EKX97274.1
YitL family protein; Belongs to the CvfB family.
       0.517
EKY02908.1
KEGG: pru:PRU_0847 3.7e-154 galE; UDP-glucose 4-epimerase K01784; Psort location: Cytoplasmic, score: 9.97; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
    
  0.410
EKY00982.1
Hypothetical protein.
  
     0.409
EKY00504.1
KEGG: pru:PRU_2201 1.6e-153 argD; acetylornithine transaminase K00818; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.408
EKX97276.1
Hypothetical protein.
       0.402
Your Current Organism:
Prevotella saccharolytica
NCBI taxonomy Id: 1127699
Other names: P. saccharolytica F0055, Prevotella saccharolytica F0055, Prevotella saccharolytica str. F0055, Prevotella saccharolytica strain F0055
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