Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EKX96136.1ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: pmz:HMPREF0659_A5055 1.3e-295 DNA topoisomerase IV subunit B; K02622 topoisomerase IV subunit B; Psort location: Cytoplasmic, score: 9.97. (645 aa)    
Predicted Functional Partners:
EKY02011.1
DNA gyrase/topoisomerase IV, A subunit; KEGG: pru:PRU_0008 0. topoisomerase GyrA/ParC subunit family protein; K02621 topoisomerase IV subunit A; Psort location: Cytoplasmic, score: 9.12.
 
 
 0.975
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
 
 
 0.956
EKX98167.1
Helicase protein; KEGG: lsp:Bsph_0793 3.8e-17 ATP-dependent helicase YqhH; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.835
EKY02854.1
Hypothetical protein.
  
 
 0.748
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
 
 0.700
EKX96137.1
KEGG: pru:PRU_2476 1.2e-194 S41 family peptidase K03797; Psort location: CytoplasmicMembrane, score: 7.88; Belongs to the peptidase S41A family.
       0.627
EKX96135.1
Hypothetical protein; KEGG: ccs:CCNA_01212 2.7e-25 dATP pyrophosphohydrolase; Psort location: Cytoplasmic, score: 8.96.
     
 0.581
secD
Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
 
  
 0.540
argS
arginine--tRNA ligase; KEGG: pmz:HMPREF0659_A6251 1.6e-265 argS; arginine--tRNA ligase K01887; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.539
EKY03129.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.498
Your Current Organism:
Prevotella saccharolytica
NCBI taxonomy Id: 1127699
Other names: P. saccharolytica F0055, Prevotella saccharolytica F0055, Prevotella saccharolytica str. F0055, Prevotella saccharolytica strain F0055
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