STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvK_2Branched-chain amino acid aminotransferase. (357 aa)    
Predicted Functional Partners:
ilvD_2
Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family.
  
 0.796
ilvD_5
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.785
ilvD_6
Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family.
  
 0.785
ilvD_3
Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family.
  
 0.785
leuA_1
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 0.784
leuA_4
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 0.771
SDE48820.1
Methyltransferase domain-containing protein.
  
 0.757
hom
Homoserine dehydrogenase.
  
 
 0.742
ilvD_4
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.739
ilvD_1
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.739
Your Current Organism:
Sporomusa acidovorans
NCBI taxonomy Id: 112900
Other names: ATCC 49682, DSM 3132, S. acidovorans, strain Mol
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.