node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SMC53152.1 | SMC53161.1 | SAMN04488500_104267 | SAMN04488500_104268 | Acetolactate synthase, small subunit. | Acetolactate synthase, large subunit. | 0.998 |
SMC53152.1 | SMC69874.1 | SAMN04488500_104267 | SAMN04488500_10711 | Acetolactate synthase, small subunit. | Branched-chain amino acid aminotransferase. | 0.705 |
SMC53152.1 | SMC75149.1 | SAMN04488500_104267 | SAMN04488500_10875 | Acetolactate synthase, small subunit. | D-alanine transaminase; Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction. | 0.694 |
SMC53152.1 | SMC78765.1 | SAMN04488500_104267 | SAMN04488500_10941 | Acetolactate synthase, small subunit. | Acetolactate synthase, large subunit. | 0.994 |
SMC53152.1 | SMC86788.1 | SAMN04488500_104267 | SAMN04488500_11151 | Acetolactate synthase, small subunit. | Acetolactate synthase, small subunit. | 0.617 |
SMC53152.1 | SMC86818.1 | SAMN04488500_104267 | SAMN04488500_11157 | Acetolactate synthase, small subunit. | Acetolactate synthase, large subunit. | 0.994 |
SMC53152.1 | SMC97537.1 | SAMN04488500_104267 | SAMN04488500_11650 | Acetolactate synthase, small subunit. | Branched-chain amino acid aminotransferase. | 0.705 |
SMC53152.1 | ilvC | SAMN04488500_104267 | SAMN04488500_11152 | Acetolactate synthase, small subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.991 |
SMC53152.1 | ilvD-2 | SAMN04488500_104267 | SAMN04488500_1478 | Acetolactate synthase, small subunit. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.936 |
SMC53152.1 | leuA | SAMN04488500_104267 | SAMN04488500_11153 | Acetolactate synthase, small subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.840 |
SMC53161.1 | SMC53152.1 | SAMN04488500_104268 | SAMN04488500_104267 | Acetolactate synthase, large subunit. | Acetolactate synthase, small subunit. | 0.998 |
SMC53161.1 | SMC69874.1 | SAMN04488500_104268 | SAMN04488500_10711 | Acetolactate synthase, large subunit. | Branched-chain amino acid aminotransferase. | 0.735 |
SMC53161.1 | SMC75149.1 | SAMN04488500_104268 | SAMN04488500_10875 | Acetolactate synthase, large subunit. | D-alanine transaminase; Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction. | 0.732 |
SMC53161.1 | SMC78765.1 | SAMN04488500_104268 | SAMN04488500_10941 | Acetolactate synthase, large subunit. | Acetolactate synthase, large subunit. | 0.587 |
SMC53161.1 | SMC86788.1 | SAMN04488500_104268 | SAMN04488500_11151 | Acetolactate synthase, large subunit. | Acetolactate synthase, small subunit. | 0.994 |
SMC53161.1 | SMC86818.1 | SAMN04488500_104268 | SAMN04488500_11157 | Acetolactate synthase, large subunit. | Acetolactate synthase, large subunit. | 0.586 |
SMC53161.1 | SMC97537.1 | SAMN04488500_104268 | SAMN04488500_11650 | Acetolactate synthase, large subunit. | Branched-chain amino acid aminotransferase. | 0.735 |
SMC53161.1 | ilvC | SAMN04488500_104268 | SAMN04488500_11152 | Acetolactate synthase, large subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.990 |
SMC53161.1 | ilvD-2 | SAMN04488500_104268 | SAMN04488500_1478 | Acetolactate synthase, large subunit. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.962 |
SMC53161.1 | leuA | SAMN04488500_104268 | SAMN04488500_11153 | Acetolactate synthase, large subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.875 |