STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OQO71477.1Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (187 aa)    
Predicted Functional Partners:
OQO71478.1
Alkyl hydroperoxide reductase subunit F; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
OQO69533.1
Thiol reductase thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.993
OQO70297.1
Thioredoxin-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.850
OQO70816.1
ferredoxin--NADP(+) reductase; Catalyzes the oxidation of ferredoxin with NADP; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.832
OQO70909.1
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 
 0.750
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 
 0.707
OQO69763.1
DNA starvation/stationary phase protection protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Dps family.
  
  
 0.688
grpE
Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...]
   
 
 0.666
OQO71242.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.656
OQO70451.1
Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutathione peroxidase family.
   
 0.656
Your Current Organism:
Enterococcus villorum
NCBI taxonomy Id: 112904
Other names: ATCC 700913 [[Enterococcus porcinus]], CCM 4887, CCUG 45025, E. villorum, Enterococcus porcinus, Enterococcus porcinus Teixeira et al. 2001, Enterococcus villorum Vancanneyt et al. 2001, JCM 11557, LMG 12287, LMG:12287, NBRC 100699, strain 88-5474
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