STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadENAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (274 aa)    
Predicted Functional Partners:
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.987
OQO70554.1
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
 
 
 0.973
ppnK
NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
 0.930
OQO68911.1
NAD-dependent protein deacylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.926
OQO70553.1
DUF1827 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.781
OQO70636.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.778
cinA
Competence/damage-inducible protein A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family.
    
 0.710
OQO68198.1
Nicotinate-nucleotide diphosphorylase (carboxylating); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family.
    
 0.687
OQO70864.1
HD domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.666
OQO70767.1
DNA mismatch repair protein MutT; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.650
Your Current Organism:
Enterococcus villorum
NCBI taxonomy Id: 112904
Other names: ATCC 700913 [[Enterococcus porcinus]], CCM 4887, CCUG 45025, E. villorum, Enterococcus porcinus, Enterococcus porcinus Teixeira et al. 2001, Enterococcus villorum Vancanneyt et al. 2001, JCM 11557, LMG 12287, LMG:12287, NBRC 100699, strain 88-5474
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