STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folXD-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase; COG1539 Dihydroneopterin aldolase. (121 aa)    
Predicted Functional Partners:
folE
COG0302 GTP cyclohydrolase I.
 
 
 0.980
AJE_11859
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.
 
 
 0.919
AJE_13045
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.
  
 
 0.887
folP
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
  
 
 0.865
AJE_08225
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
  
 
 0.865
AJE_02841
Hypothetical protein; COG1090 Predicted nucleoside-diphosphate sugar epimerase.
      0.847
AJE_10804
Metallophosphoesterase; COG1409 Predicted phosphohydrolases.
     
 0.768
AJE_14295
COG0285 Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.
  
 
 0.750
AJE_02821
Hypothetical protein.
       0.594
AJE_02826
Response regulator in two-component regulatory system with PhoQ; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
       0.594
Your Current Organism:
Alishewanella jeotgali
NCBI taxonomy Id: 1129374
Other names: A. jeotgali KCTC 22429, Alishewanella jeotgali KCTC 22429, Alishewanella jeotgali MS1, Alishewanella jeotgali str. KCTC 22429, Alishewanella jeotgali strain KCTC 22429, Alishewanella sp. MS1
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