AJE_06866 protein (Alishewanella jeotgali) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

AJE_06866

Phage protein; COG3514 Uncharacterized protein conserved in bacteria. (93 aa)

Predicted Functional Partners:

AJE_06861

0.990

AJE_06816

0.960

AJE_06871

0.696

AJE_06801

0.684

AJE_07805

0.482

AJE_06856

0.445

AJE_00290

0.427

AJE_06791

0.402

Your Current Organism:

Alishewanella jeotgali

NCBI taxonomy Id: 1129374
Other names: A. jeotgali KCTC 22429, Alishewanella jeotgali KCTC 22429, Alishewanella jeotgali MS1, Alishewanella jeotgali str. KCTC 22429, Alishewanella jeotgali strain KCTC 22429, Alishewanella sp. MS1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
AJE_00290	AJE_06816	Hypothetical protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.	COG2929 Uncharacterized protein conserved in bacteria.	0.406
AJE_00290	AJE_06861	Hypothetical protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.	COG2929 Uncharacterized protein conserved in bacteria.	0.451
AJE_00290	AJE_06866	Hypothetical protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.	Phage protein; COG3514 Uncharacterized protein conserved in bacteria.	0.427
AJE_06791	AJE_06801	COG5304 Uncharacterized protein conserved in bacteria.	Hypothetical protein.	0.788
AJE_06791	AJE_06816	COG5304 Uncharacterized protein conserved in bacteria.	COG2929 Uncharacterized protein conserved in bacteria.	0.469
AJE_06791	AJE_06861	COG5304 Uncharacterized protein conserved in bacteria.	COG2929 Uncharacterized protein conserved in bacteria.	0.437
AJE_06791	AJE_06866	COG5304 Uncharacterized protein conserved in bacteria.	Phage protein; COG3514 Uncharacterized protein conserved in bacteria.	0.402
AJE_06791	AJE_07805	COG5304 Uncharacterized protein conserved in bacteria.	Transcriptional regulator.	0.521
AJE_06801	AJE_06791	Hypothetical protein.	COG5304 Uncharacterized protein conserved in bacteria.	0.788
AJE_06801	AJE_06816	Hypothetical protein.	COG2929 Uncharacterized protein conserved in bacteria.	0.419
AJE_06801	AJE_06861	Hypothetical protein.	COG2929 Uncharacterized protein conserved in bacteria.	0.402
AJE_06801	AJE_06866	Hypothetical protein.	Phage protein; COG3514 Uncharacterized protein conserved in bacteria.	0.684
AJE_06801	AJE_06871	Hypothetical protein.	COG5304 Uncharacterized protein conserved in bacteria.	0.788
AJE_06801	AJE_07805	Hypothetical protein.	Transcriptional regulator.	0.610
AJE_06816	AJE_00290	COG2929 Uncharacterized protein conserved in bacteria.	Hypothetical protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.	0.406
AJE_06816	AJE_06791	COG2929 Uncharacterized protein conserved in bacteria.	COG5304 Uncharacterized protein conserved in bacteria.	0.469
AJE_06816	AJE_06801	COG2929 Uncharacterized protein conserved in bacteria.	Hypothetical protein.	0.419
AJE_06816	AJE_06866	COG2929 Uncharacterized protein conserved in bacteria.	Phage protein; COG3514 Uncharacterized protein conserved in bacteria.	0.960
AJE_06816	AJE_06871	COG2929 Uncharacterized protein conserved in bacteria.	COG5304 Uncharacterized protein conserved in bacteria.	0.479
AJE_06816	AJE_07805	COG2929 Uncharacterized protein conserved in bacteria.	Transcriptional regulator.	0.408

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

33

average node degree:

6

avg. local clustering coefficient:

0.925

expected number of edges:

46

PPI enrichment p-value:

0.981

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042128

Nitrate assimilation

4 of 16

2.67

3.23

9.14e-07

GO:0034975

Protein folding in endoplasmic reticulum

3 of 9

2.79

2.54

2.14e-05

GO:0043436

Oxoacid metabolic process

6 of 1303

0.93

0.59

0.0164

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0050464

Nitrate reductase (NADPH) activity

4 of 4

3.27

4.49

6.87e-09

GO:0043546

Molybdopterin cofactor binding

4 of 10

2.87

4.16

1.96e-08

GO:0030151

Molybdenum ion binding

4 of 15

2.7

3.9

4.74e-08

GO:0071949

FAD binding

6 of 147

1.88

3.2

2.54e-08

GO:0016972

Thiol oxidase activity

2 of 4

2.97

1.69

0.00086

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:25710

Nitrate reductase activity

5 of 5

3.27

6.11

6.94e-12

CL:25684

Mixed, incl. Sulfur metabolism, and Protein disulfide isomerase activity

8 of 132

2.05

4.86

2.23e-12

CL:25892

Protein disulfide isomerase activity

3 of 13

2.63

2.54

1.94e-05

CL:25894

Protein disulfide isomerase activity, and ERO1-like superfamily

2 of 8

2.67

1.44

0.0024

CL:23966

Tryptophan synthase activity, and Indole-3-glycerol phosphate synthase

2 of 8

2.67

1.44

0.0024

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00910

Nitrogen metabolism

4 of 104

1.86

2.06

3.67e-05

map04141

Protein processing in endoplasmic reticulum

4 of 402

1.27

0.96

0.0035

map00400

Phenylalanine, tyrosine and tryptophan biosynthesis

2 of 77

1.69

0.71

0.0415

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0274

FAD

4 of 102

1.87

2.0

5.56e-05

KW-0349

Heme

3 of 97

1.76

1.35

0.0016

KW-1015

Disulfide bond

2 of 58

1.81

0.84

0.0235

KW-0560

Oxidoreductase

3 of 325

1.24

0.68

0.0261

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00970

Oxidoreductase FAD-binding domain

5 of 15

2.79

4.91

6.04e-10

PF03404

Mo-co oxidoreductase dimerisation domain

4 of 9

2.92

4.01

4.10e-08

PF00174

Oxidoreductase molybdopterin binding domain

4 of 10

2.87

3.99

4.10e-08

PF00175

Oxidoreductase NAD-binding domain

4 of 26

2.46

3.19

7.81e-07

PF04137

Endoplasmic Reticulum Oxidoreductin 1 (ERO1)

2 of 2

3.27

1.72

0.00081

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR008333

Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain

5 of 15

2.79

4.7

1.53e-09

IPR008335

Eukaryotic molybdopterin oxidoreductase

4 of 9

2.92

3.79

1.04e-07

IPR005066

Moybdenum cofactor oxidoreductase, dimerisation

4 of 9

2.92

3.79

1.04e-07

IPR036374

Oxidoreductase, molybdopterin-binding domain superfamily

4 of 10

2.87

3.78

1.04e-07

IPR000572

Oxidoreductase, molybdopterin-binding domain

4 of 10

2.87

3.78

1.04e-07

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01117

Cytochrome b5-like Heme/Steroid binding domain

5 of 52

2.25

3.67

3.35e-08

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (16%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About