STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AJE_07935methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (148 aa)    
Predicted Functional Partners:
AJE_07930
AraC family transcriptional regulator; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase.
 
 0.981
AJE_08642
DNA-O6-methylguanine--protein-cysteine S-methyltransferase/transcriptional regulator Ada; COG2169 Adenosine deaminase.
 
 0.980
queG
Putative iron-sulfur cluster binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.
      0.910
lpxB
lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
      0.900
queA
S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
    
  0.578
AJE_04245
Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.
 
   
 0.551
AJE_04485
COG0589 Universal stress protein UspA and related nucleotide-binding proteins.
  
    0.516
AJE_01781
COG0589 Universal stress protein UspA and related nucleotide-binding proteins.
  
    0.511
AJE_07925
Transposase Tn5 dimerization subunit.
       0.494
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.476
Your Current Organism:
Alishewanella jeotgali
NCBI taxonomy Id: 1129374
Other names: A. jeotgali KCTC 22429, Alishewanella jeotgali KCTC 22429, Alishewanella jeotgali MS1, Alishewanella jeotgali str. KCTC 22429, Alishewanella jeotgali strain KCTC 22429, Alishewanella sp. MS1
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