STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AJE_17059COG2828 Uncharacterized protein conserved in bacteria. (395 aa)    
Predicted Functional Partners:
AJE_17054
Aconitate hydratase; COG1048 Aconitase A.
 
 
 0.996
AJE_11534
Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; COG1049 Aconitase B; Belongs to the aconitase/IPM isomerase family.
    
 0.904
prpB
2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
 
  
 0.817
AJE_17049
COG0372 Citrate synthase; Belongs to the citrate synthase family.
 
  
 0.747
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
 
 
   0.725
AJE_02146
Hypothetical protein.
    
 0.615
AJE_17039
COG1802 Transcriptional regulators.
 
  
 0.535
AJE_16794
COG0372 Citrate synthase; Belongs to the citrate synthase family.
  
  
 0.510
AJE_02311
COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.
    
 0.495
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
    
 0.495
Your Current Organism:
Alishewanella jeotgali
NCBI taxonomy Id: 1129374
Other names: A. jeotgali KCTC 22429, Alishewanella jeotgali KCTC 22429, Alishewanella jeotgali MS1, Alishewanella jeotgali str. KCTC 22429, Alishewanella jeotgali strain KCTC 22429, Alishewanella sp. MS1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.