STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hmgLhydroxymethylglutaryl-CoA lyase. (310 aa)    
Predicted Functional Partners:
mhpF
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
  
 0.931
liuC
methylglutaconyl-CoA hydratase.
 
  0.852
atuE
isohexenylglutaconyl-CoA hydratase.
 
 
  0.792
scoA
3-oxoacid CoA-transferase subunit A.
  
 
 0.788
lpsJ
succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B.
  
 
 0.778
fadA
acetyl-CoA acyltransferase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
  
 
 0.770
GPLA_1449
L-carnitine dehydratase; Belongs to the CoA-transferase III family.
  
  0.767
leuC-2
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
 
 0.758
fadI
3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
  
 
 0.747
GPLA_1048
Hydroxymethylglutaryl-CoA lyase, mitochondrial.
  
  
 
0.744
Your Current Organism:
Paraglaciecola polaris
NCBI taxonomy Id: 1129793
Other names: Glaciecola polaris LMG 21857, Glaciecola polaris str. LMG 21857, Glaciecola polaris strain LMG 21857, P. polaris LMG 21857, Paraglaciecola polaris LMG 21857
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