STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mprFMembrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. (339 aa)    
Predicted Functional Partners:
AJT49965.1
Glycosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.949
AJT49964.1
1,2-diacylglycerol 3-glucosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.918
AJT49967.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.745
AJT51080.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.741
AJT51265.1
IpaB/EvcA family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.694
AJT49783.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.654
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.606
AJT50896.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.542
AJT49962.1
Phosphocarrier protein HPr; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.536
lexA
LexA family transcriptional regulator; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
 
   
 0.502
Your Current Organism:
Lactobacillus mucosae
NCBI taxonomy Id: 1130798
Other names: L. mucosae LM1, Lactobacillus mucosae LM1, Lactobacillus mucosae str. LM1, Lactobacillus mucosae strain LM1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.