STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AJT50634.13'-5' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)    
Predicted Functional Partners:
cas1
CRISPR-associated protein Cse1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
     0.952
AJT50636.1
CRISPR-associated protein CasE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.944
AJT50637.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.936
AJT50638.1
CRISPR-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.935
AJT50639.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.919
AJT50640.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.919
AJT50641.1
CRISPR-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.919
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 
 0.432
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.426
Your Current Organism:
Lactobacillus mucosae
NCBI taxonomy Id: 1130798
Other names: L. mucosae LM1, Lactobacillus mucosae LM1, Lactobacillus mucosae str. LM1, Lactobacillus mucosae strain LM1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.