STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (299 aa)    
Predicted Functional Partners:
AFV04438.1
Threonine synthase.
 
 0.999
AFV04971.1
Homoserine dehydrogenase.
 
 0.997
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
 
    
 0.911
AFV05294.1
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.884
AFV05725.1
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.884
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.870
AFV06066.1
Aspartokinase; Belongs to the aspartokinase family.
 
 
 0.846
AFV05755.1
Serine acetyltransferase.
     
 0.830
AFV06175.1
L-serine dehydratase, alpha subunit; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.827
AFV06176.1
L-serine dehydratase, beta subunit; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.827
Your Current Organism:
Dehalobacter sp. CF
NCBI taxonomy Id: 1131462
Other names: D. sp. CF
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.