STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (345 aa)    
Predicted Functional Partners:
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
 
 0.999
BAZO_06744
COG0147 Anthranilate/para-aminobenzoate synthases component I.
 
 0.998
BAZO_06589
COG0512 Anthranilate/para-aminobenzoate synthases component II.
 
 0.997
trpF
COG0135 Phosphoribosylanthranilate isomerase; Belongs to the TrpF family.
 
 
 0.997
trpC
COG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
 
 0.997
BAZO_10156
COG0134 Indole-3-glycerol phosphate synthase.
 
 0.982
trpF-2
COG0135 Phosphoribosylanthranilate isomerase; Belongs to the TrpF family.
 
 
 0.981
trpA
Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
  
 0.968
trpB-2
Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
 
 0.968
trpB
Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
 
 0.967
Your Current Organism:
Bacillus azotoformans
NCBI taxonomy Id: 1131731
Other names: B. azotoformans LMG 9581, Bacillus azotoformans ATCC 29788, Bacillus azotoformans IFO 15712, Bacillus azotoformans LMG 9581, Bacillus azotoformans NBRC 15712, Bacillus azotoformans str. LMG 9581, Bacillus azotoformans strain LMG 9581
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