STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
holACOG1466 DNA polymerase III, delta subunit. (340 aa)    
Predicted Functional Partners:
BAZO_03046
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 
 0.988
dnaX
DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
 
 0.979
BAZO_13659
DNA polymerase III subunit delta; COG0470 ATPase involved in DNA replication.
 
 
 0.966
BAZO_13754
DNA polymerase III subunit delta; COG0470 ATPase involved in DNA replication.
 
 
 0.950
dinG
Bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; 3'-5' exonuclease.
    
 0.864
BAZO_14444
DNA internalization-related competence protein ComEC/Rec2; COG0658 Predicted membrane metal-binding protein.
 
   
 0.749
uvrC
Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
 
  
 0.732
ligA
NAD-dependent DNA ligase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
     
 0.722
polC
DNA polymerase III PolC; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
    
 0.702
BAZO_20433
Exonuclease; COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases.
    
 0.694
Your Current Organism:
Bacillus azotoformans
NCBI taxonomy Id: 1131731
Other names: B. azotoformans LMG 9581, Bacillus azotoformans ATCC 29788, Bacillus azotoformans IFO 15712, Bacillus azotoformans LMG 9581, Bacillus azotoformans NBRC 15712, Bacillus azotoformans str. LMG 9581, Bacillus azotoformans strain LMG 9581
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