STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (269 aa)    
Predicted Functional Partners:
nadD
NadD; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.964
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
  
 0.929
EHQ62045.1
COG0846 NAD-dependent protein deacetylases, SIR2 family.
    
 0.826
EHQ61996.1
COG0846 NAD-dependent protein deacetylases, SIR2 family.
    
 0.826
EHQ59701.1
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
  
 
 0.779
EHQ60946.1
Hypothetical protein; Belongs to the UPF0403 family.
       0.732
cinA
CinA-like protein; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family.
    
 0.694
EHQ64019.1
Amino acid adenylation protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.
  
  
 0.635
EHQ60943.1
COG2081 Predicted flavoproteins.
       0.616
EHQ62753.1
COG0515 Serine/threonine protein kinase.
  
  
 0.586
Your Current Organism:
Paenibacillus dendritiformis
NCBI taxonomy Id: 1131935
Other names: P. dendritiformis C454, Paenibacillus dendritiformis C454, Paenibacillus dendritiformis str. C454, Paenibacillus dendritiformis strain C454
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