AC579_2510 protein (Pseudocercospora musae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

AC579_2510

Peptidase A1 domain-containing protein; Belongs to the zinc-containing alcohol dehydrogenase family. (920 aa)

Predicted Functional Partners:

AC579_3508

0.765

AC579_7277

0.699

AC579_3544

0.674

AC579_8623

0.628

AC579_7271

0.576

AC579_3630

0.572

AC579_2800

0.566

AC579_6838

0.560

AC579_2818

0.560

AC579_5904

0.560

Your Current Organism:

Pseudocercospora musae

NCBI taxonomy Id: 113226
Other names: Mycosphaerella musicola, Mycosphaerella musicola R. Leach, P. musae

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AC579_2510	AC579_2800	A0A139I4C3	A0A139IKI2	Peptidase A1 domain-containing protein; Belongs to the zinc-containing alcohol dehydrogenase family.	PKS_ER domain-containing protein.	0.566
AC579_2510	AC579_2818	A0A139I4C3	A0A139IKP7	Peptidase A1 domain-containing protein; Belongs to the zinc-containing alcohol dehydrogenase family.	Aldedh domain-containing protein.	0.560
AC579_2510	AC579_3508	A0A139I4C3	A0A139I3A8	Peptidase A1 domain-containing protein; Belongs to the zinc-containing alcohol dehydrogenase family.	Uncharacterized protein.	0.765
AC579_2510	AC579_3544	A0A139I4C3	A0A139IVY0	Peptidase A1 domain-containing protein; Belongs to the zinc-containing alcohol dehydrogenase family.	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	0.674
AC579_2510	AC579_3630	A0A139I4C3	A0A139ISV3	Peptidase A1 domain-containing protein; Belongs to the zinc-containing alcohol dehydrogenase family.	PKS_ER domain-containing protein.	0.572
AC579_2510	AC579_5904	A0A139I4C3	A0A139ITJ3	Peptidase A1 domain-containing protein; Belongs to the zinc-containing alcohol dehydrogenase family.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.560
AC579_2510	AC579_6838	A0A139I4C3	A0A139I7Y2	Peptidase A1 domain-containing protein; Belongs to the zinc-containing alcohol dehydrogenase family.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.560
AC579_2510	AC579_7271	A0A139I4C3	A0A139HLL2	Peptidase A1 domain-containing protein; Belongs to the zinc-containing alcohol dehydrogenase family.	PKS_ER domain-containing protein.	0.576
AC579_2510	AC579_7277	A0A139I4C3	A0A139GVZ2	Peptidase A1 domain-containing protein; Belongs to the zinc-containing alcohol dehydrogenase family.	Fe-ADH domain-containing protein.	0.699
AC579_2510	AC579_8623	A0A139I4C3	A0A139IFI7	Peptidase A1 domain-containing protein; Belongs to the zinc-containing alcohol dehydrogenase family.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.628
AC579_2800	AC579_2510	A0A139IKI2	A0A139I4C3	PKS_ER domain-containing protein.	Peptidase A1 domain-containing protein; Belongs to the zinc-containing alcohol dehydrogenase family.	0.566
AC579_2800	AC579_2818	A0A139IKI2	A0A139IKP7	PKS_ER domain-containing protein.	Aldedh domain-containing protein.	0.442
AC579_2800	AC579_3508	A0A139IKI2	A0A139I3A8	PKS_ER domain-containing protein.	Uncharacterized protein.	0.731
AC579_2800	AC579_3630	A0A139IKI2	A0A139ISV3	PKS_ER domain-containing protein.	PKS_ER domain-containing protein.	0.578
AC579_2800	AC579_5904	A0A139IKI2	A0A139ITJ3	PKS_ER domain-containing protein.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.442
AC579_2800	AC579_6838	A0A139IKI2	A0A139I7Y2	PKS_ER domain-containing protein.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.442
AC579_2800	AC579_7271	A0A139IKI2	A0A139HLL2	PKS_ER domain-containing protein.	PKS_ER domain-containing protein.	0.559
AC579_2800	AC579_7277	A0A139IKI2	A0A139GVZ2	PKS_ER domain-containing protein.	Fe-ADH domain-containing protein.	0.579
AC579_2800	AC579_8623	A0A139IKI2	A0A139IFI7	PKS_ER domain-containing protein.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.442
AC579_2818	AC579_2510	A0A139IKP7	A0A139I4C3	Aldedh domain-containing protein.	Peptidase A1 domain-containing protein; Belongs to the zinc-containing alcohol dehydrogenase family.	0.560

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

54

average node degree:

9.82

avg. local clustering coefficient:

0.982

expected number of edges:

24

PPI enrichment p-value:

9.83e-08

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006325

Chromatin organization

5 of 188

1.32

0.88

0.0078

GO:0006357

Regulation of transcription by RNA polymerase II

5 of 313

1.1

0.69

0.0149

GO:0016570

Histone modification

3 of 83

1.45

0.68

0.0371

GO:0006355

Regulation of transcription, DNA-templated

6 of 450

1.02

0.65

0.0137

GO:0006338

Chromatin remodeling

3 of 91

1.41

0.64

0.0450

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004402

Histone acetyltransferase activity

3 of 15

2.19

1.45

0.0018

GO:0140064

Peptide crotonyltransferase activity

2 of 3

2.72

1.25

0.0054

GO:0010484

H3 histone acetyltransferase activity

2 of 3

2.72

1.25

0.0054

GO:0030527

Structural constituent of chromatin

2 of 10

2.19

0.97

0.0157

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000786

Nucleosome

2 of 13

2.08

0.74

0.0427

GO:0005694

Chromosome

5 of 319

1.09

0.71

0.0117

GO:0000124

SAGA complex

2 of 16

1.99

0.71

0.0465

GO:0005634

Nucleus

10 of 2090

0.57

0.42

0.0053

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-9018519

Estrogen-dependent gene expression

6 of 37

2.1

3.83

4.52e-09

MAP-8939211

ESR-mediated signaling

6 of 43

2.04

3.7

5.17e-09

MAP-9006931

Signaling by Nuclear Receptors

6 of 95

1.69

2.54

3.04e-07

MAP-2299718

Condensation of Prophase Chromosomes

2 of 7

2.35

1.09

0.0097

MAP-162582

Signal Transduction

8 of 603

1.01

1.05

1.95e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0544

Nucleosome core

2 of 6

2.41

1.26

0.0048

KW-0539

Nucleus

5 of 289

1.13

0.84

0.0041

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR039355

Transcription factor GATA

2 of 2

2.89

0.91

0.0224

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00401

Zinc finger binding to DNA consensus sequence [AT]GATA[AG]

2 of 5

2.49

1.11

0.0095

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (10%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About