AC579_4044 protein (Pseudocercospora musae) - STRING interaction network

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second shell of interactors

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a 3D structure is known or predicted

Edges:

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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Score

AC579_4044

Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1074 aa)

Predicted Functional Partners:

AC579_7731

0.993

AC579_3033

0.974

AC579_9005

0.934

AC579_9000

0.934

AC579_10497

0.910

AC579_1405

0.910

AC579_7929

0.910

AC579_3265

0.882

AC579_6386

0.872

AC579_5915

0.863

Your Current Organism:

Pseudocercospora musae

NCBI taxonomy Id: 113226
Other names: Mycosphaerella musicola, Mycosphaerella musicola R. Leach, P. musae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AC579_10497	AC579_3033	A0A139IAV8	A0A139I4B9	Uncharacterized protein.	UBA domain-containing protein.	0.865
AC579_10497	AC579_4044	A0A139IAV8	A0A139IE14	Uncharacterized protein.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.910
AC579_10497	AC579_9000	A0A139IAV8	A0A139H6M7	Uncharacterized protein.	Uncharacterized protein.	0.581
AC579_10497	AC579_9005	A0A139IAV8	A0A139H6K9	Uncharacterized protein.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.581
AC579_1405	AC579_3033	A0A139IFS9	A0A139I4B9	Uncharacterized protein.	UBA domain-containing protein.	0.865
AC579_1405	AC579_4044	A0A139IFS9	A0A139IE14	Uncharacterized protein.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.910
AC579_1405	AC579_9000	A0A139IFS9	A0A139H6M7	Uncharacterized protein.	Uncharacterized protein.	0.581
AC579_1405	AC579_9005	A0A139IFS9	A0A139H6K9	Uncharacterized protein.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.581
AC579_3033	AC579_10497	A0A139I4B9	A0A139IAV8	UBA domain-containing protein.	Uncharacterized protein.	0.865
AC579_3033	AC579_1405	A0A139I4B9	A0A139IFS9	UBA domain-containing protein.	Uncharacterized protein.	0.865
AC579_3033	AC579_4044	A0A139I4B9	A0A139IE14	UBA domain-containing protein.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.974
AC579_3033	AC579_5915	A0A139I4B9	A0A139IT07	UBA domain-containing protein.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	0.703
AC579_3033	AC579_7929	A0A139I4B9	A0A139IK98	UBA domain-containing protein.	Uncharacterized protein.	0.865
AC579_3033	AC579_9000	A0A139I4B9	A0A139H6M7	UBA domain-containing protein.	Uncharacterized protein.	0.998
AC579_3033	AC579_9005	A0A139I4B9	A0A139H6K9	UBA domain-containing protein.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.998
AC579_3265	AC579_4044	A0A139IDG0	A0A139IE14	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.882
AC579_3265	AC579_5915	A0A139IDG0	A0A139IT07	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	0.861
AC579_3265	AC579_6386	A0A139IDG0	A0A139IJA1	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.764
AC579_3265	AC579_7731	A0A139IDG0	A0A139HRG7	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.963
AC579_3265	AC579_9000	A0A139IDG0	A0A139H6M7	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.564

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

12

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006914

Autophagy

7 of 78

1.92

3.58

2.43e-09

GO:0030242

Autophagy of peroxisome

3 of 4

2.84

2.43

3.66e-05

GO:0016236

Macroautophagy

4 of 39

1.97

2.01

7.51e-05

GO:0015031

Protein transport

6 of 431

1.11

0.96

0.00079

GO:0006810

Transport

9 of 1132

0.86

0.8

8.39e-05

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0034272

Phosphatidylinositol 3-kinase complex, class III, type II

4 of 4

2.96

4.01

4.19e-08

GO:0034271

Phosphatidylinositol 3-kinase complex, class III, type I

4 of 4

2.96

4.01

4.19e-08

GO:0005770

Late endosome

4 of 41

1.95

2.36

9.70e-06

GO:0005768

Endosome

6 of 160

1.54

2.16

7.62e-07

GO:0031410

Cytoplasmic vesicle

8 of 297

1.39

2.08

4.19e-08

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:11291

Autophagy - other, and SNARE complex assembly

8 of 34

2.33

6.44

1.03e-14

CL:11297

Autophagy, and Phosphatidylinositol 3-kinase complex, class III, type I

5 of 14

2.52

4.53

1.45e-09

CL:8217

Mixed, incl. HOPS complex, and VPS9 domain

3 of 29

1.98

1.57

0.00075

CL:11299

Ubiquitin-like autophagy protein Apg12 , and Autophagy

2 of 7

2.42

1.22

0.0056

CL:8218

HOPS complex, and phosphatidylinositol-5-phosphate binding

2 of 18

2.01

0.84

0.0265

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04136

Autophagy - other

5 of 38

2.08

3.37

5.96e-08

map04138

Autophagy - yeast

6 of 97

1.75

2.85

5.96e-08

map04145

Phagosome

3 of 81

1.53

1.08

0.0041

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-9612973

Autophagy

7 of 78

1.92

3.75

6.84e-10

MAP-1632852

Macroautophagy

7 of 78

1.92

3.75

6.84e-10

MAP-1483255

PI Metabolism

4 of 36

2.01

2.27

2.10e-05

MAP-5668599

RHO GTPases Activate NADPH Oxidases

3 of 11

2.4

2.17

8.02e-05

MAP-1660517

Synthesis of PIPs at the late endosome membrane

3 of 11

2.4

2.17

8.02e-05

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0034272

Phosphatidylinositol 3-kinase complex, class III, type II

5 of 6

2.88

5.16

2.39e-10

GOCC:0034271

Phosphatidylinositol 3-kinase complex, class III, type I

4 of 4

2.96

4.28

1.31e-08

GOCC:0044232

Organelle membrane contact site

3 of 25

2.04

1.75

0.00034

GOCC:0000421

Autophagosome membrane

2 of 4

2.66

1.53

0.0016

GOCC:0071561

Nucleus-vacuole junction

2 of 5

2.57

1.47

0.0020

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0449

Lipoprotein

2 of 2

2.96

1.58

0.0014

KW-0072

Autophagy

2 of 14

2.12

0.98

0.0144

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF04110

Ubiquitin-like autophagy protein Apg12

2 of 3

2.79

1.1

0.0100

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR045162

Serine/threonine-protein kinase Vps15-like

2 of 2

2.96

0.98

0.0172

IPR004241

Autophagy protein Atg8 ubiquitin-like

2 of 2

2.96

0.98

0.0172

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