AC579_4173 protein (Pseudocercospora musae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

AC579_4173

PHD domain-containing protein. (289 aa)

Predicted Functional Partners:

AC579_7985

0.718

AC579_1541

0.585

AC579_5022

0.561

AC579_3036

0.542

AC579_2047

0.542

AC579_7193

0.505

AC579_9469

0.505

AC579_6481

0.505

AC579_5320

0.505

AC579_6135

0.499

Your Current Organism:

Pseudocercospora musae

NCBI taxonomy Id: 113226
Other names: Mycosphaerella musicola, Mycosphaerella musicola R. Leach, P. musae

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AC579_1541	AC579_2047	A0A139IM80	A0A139IC21	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Enhancer of polycomb-like protein.	0.993
AC579_1541	AC579_3036	A0A139IM80	A0A139I490	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	TAF domain-containing protein.	0.993
AC579_1541	AC579_4173	A0A139IM80	A0A139IFK1	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	PHD domain-containing protein.	0.585
AC579_1541	AC579_5022	A0A139IM80	A0A139I8D7	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Myb-like domain-containing protein.	0.988
AC579_1541	AC579_5320	A0A139IM80	A0A139IT43	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.932
AC579_1541	AC579_6481	A0A139IM80	A0A139IAB2	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.932
AC579_1541	AC579_7193	A0A139IM80	A0A139I485	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.981
AC579_1541	AC579_7985	A0A139IM80	A0A139I014	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.984
AC579_1541	AC579_9469	A0A139IM80	A0A139I9T4	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.916
AC579_2047	AC579_1541	A0A139IC21	A0A139IM80	Enhancer of polycomb-like protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.993
AC579_2047	AC579_4173	A0A139IC21	A0A139IFK1	Enhancer of polycomb-like protein.	PHD domain-containing protein.	0.542
AC579_2047	AC579_5022	A0A139IC21	A0A139I8D7	Enhancer of polycomb-like protein.	Myb-like domain-containing protein.	0.993
AC579_2047	AC579_5320	A0A139IC21	A0A139IT43	Enhancer of polycomb-like protein.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.853
AC579_2047	AC579_6481	A0A139IC21	A0A139IAB2	Enhancer of polycomb-like protein.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.853
AC579_2047	AC579_7193	A0A139IC21	A0A139I485	Enhancer of polycomb-like protein.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.988
AC579_2047	AC579_7985	A0A139IC21	A0A139I014	Enhancer of polycomb-like protein.	Uncharacterized protein.	0.992
AC579_2047	AC579_9469	A0A139IC21	A0A139I9T4	Enhancer of polycomb-like protein.	Uncharacterized protein.	0.821
AC579_3036	AC579_1541	A0A139I490	A0A139IM80	TAF domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.993
AC579_3036	AC579_4173	A0A139I490	A0A139IFK1	TAF domain-containing protein.	PHD domain-containing protein.	0.542
AC579_4173	AC579_1541	A0A139IFK1	A0A139IM80	PHD domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.585

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

26

average node degree:

4.73

avg. local clustering coefficient:

0.878

expected number of edges:

25

PPI enrichment p-value:

0.455

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006351

Transcription, DNA-templated

6 of 143

1.62

2.02

8.08e-06

GO:0006383

Transcription by RNA polymerase III

3 of 19

2.19

1.83

0.00030

GO:0009059

Macromolecule biosynthetic process

8 of 669

1.07

1.13

2.36e-05

GO:0044271

Cellular nitrogen compound biosynthetic process

8 of 730

1.03

1.05

3.71e-05

GO:0044249

Cellular biosynthetic process

9 of 1207

0.87

0.82

6.18e-05

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003677

DNA binding

7 of 547

1.1

1.02

0.00035

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000127

Transcription factor TFIIIC complex

3 of 4

2.87

2.73

1.00e-05

GO:0005667

Transcription regulator complex

5 of 71

1.84

2.37

4.89e-06

GO:0000428

DNA-directed RNA polymerase complex

3 of 81

1.56

0.94

0.0104

GO:0005763

Mitochondrial small ribosomal subunit

2 of 29

1.83

0.73

0.0394

GO:0032991

Protein-containing complex

9 of 1827

0.69

0.56

0.00083

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3529

RNA Polymerase III Transcription Initiation From Type 1 Promoter

4 of 18

2.34

2.71

5.93e-06

CL:3271

Transcription, DNA-templated, and Mediator complex

5 of 160

1.49

1.51

0.00016

CL:3532

RNA polymerase III complex, and Transcription factor TFIIIB complex

2 of 12

2.21

0.87

0.0241

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-76066

RNA Polymerase III Transcription Initiation From Type 2 Promoter

6 of 24

2.39

4.91

1.09e-10

MAP-76061

RNA Polymerase III Transcription Initiation From Type 1 Promoter

6 of 24

2.39

4.91

1.09e-10

MAP-76046

RNA Polymerase III Transcription Initiation

6 of 27

2.34

4.84

1.09e-10

MAP-74158

RNA Polymerase III Transcription

6 of 27

2.34

4.84

1.09e-10

MAP-74160

Gene expression (Transcription)

7 of 606

1.06

1.04

8.76e-05

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (14%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About