node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AC579_10022 | AC579_2913 | A0A139IGW2 | A0A139IUP6 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | Uncharacterized protein. | 0.794 |
AC579_10022 | AC579_538 | A0A139IGW2 | A0A139IR93 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | Uncharacterized protein. | 0.861 |
AC579_10022 | AC579_6190 | A0A139IGW2 | A0A139ISR0 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | BRCT domain-containing protein. | 0.964 |
AC579_10022 | AC579_6301 | A0A139IGW2 | A0A139IPV0 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.983 |
AC579_10022 | AC579_6659 | A0A139IGW2 | A0A139IPX7 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | AAA_23 domain-containing protein. | 0.970 |
AC579_10022 | AC579_7145 | A0A139IGW2 | A0A139INE8 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | Histone H2A; Belongs to the histone H2A family. | 0.811 |
AC579_10022 | AC579_8667 | A0A139IGW2 | A0A139I3Z6 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | FHA domain-containing protein. | 0.992 |
AC579_2913 | AC579_10022 | A0A139IUP6 | A0A139IGW2 | Uncharacterized protein. | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | 0.794 |
AC579_2913 | AC579_538 | A0A139IUP6 | A0A139IR93 | Uncharacterized protein. | Uncharacterized protein. | 0.761 |
AC579_2913 | AC579_5783 | A0A139IUP6 | A0A139IRJ1 | Uncharacterized protein. | WD_REPEATS_REGION domain-containing protein. | 0.651 |
AC579_2913 | AC579_6190 | A0A139IUP6 | A0A139ISR0 | Uncharacterized protein. | BRCT domain-containing protein. | 0.854 |
AC579_2913 | AC579_6301 | A0A139IUP6 | A0A139IPV0 | Uncharacterized protein. | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.693 |
AC579_2913 | AC579_6659 | A0A139IUP6 | A0A139IPX7 | Uncharacterized protein. | AAA_23 domain-containing protein. | 0.692 |
AC579_2913 | AC579_7037 | A0A139IUP6 | A0A139IA78 | Uncharacterized protein. | SMC_N domain-containing protein. | 0.768 |
AC579_2913 | AC579_7145 | A0A139IUP6 | A0A139INE8 | Uncharacterized protein. | Histone H2A; Belongs to the histone H2A family. | 0.748 |
AC579_2913 | AC579_8667 | A0A139IUP6 | A0A139I3Z6 | Uncharacterized protein. | FHA domain-containing protein. | 0.765 |
AC579_2913 | AC579_9930 | A0A139IUP6 | A0A139I3L2 | Uncharacterized protein. | SPRY domain-containing protein. | 0.658 |
AC579_538 | AC579_10022 | A0A139IR93 | A0A139IGW2 | Uncharacterized protein. | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | 0.861 |
AC579_538 | AC579_2913 | A0A139IR93 | A0A139IUP6 | Uncharacterized protein. | Uncharacterized protein. | 0.761 |
AC579_538 | AC579_6190 | A0A139IR93 | A0A139ISR0 | Uncharacterized protein. | BRCT domain-containing protein. | 0.990 |