| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EJT05622.1 | EJT05820.1 | RCCGE510_10335 | RCCGE510_07826 | precorrin-3B C17-methyltransferase; COG2073 Cobalamin biosynthesis protein CbiG. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.896 |
| EJT05622.1 | EJT06093.1 | RCCGE510_10335 | RCCGE510_06147 | precorrin-3B C17-methyltransferase; COG2073 Cobalamin biosynthesis protein CbiG. | COG2875 Precorrin-4 methylase; Belongs to the precorrin methyltransferase family. | 0.980 |
| EJT05622.1 | EJT06094.1 | RCCGE510_10335 | RCCGE510_06152 | precorrin-3B C17-methyltransferase; COG2073 Cobalamin biosynthesis protein CbiG. | Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; COG2241 Precorrin-6B methylase 1. | 0.986 |
| EJT05622.1 | EJT06095.1 | RCCGE510_10335 | RCCGE510_06157 | precorrin-3B C17-methyltransferase; COG2073 Cobalamin biosynthesis protein CbiG. | COG2099 Precorrin-6x reductase. | 0.971 |
| EJT05622.1 | EJT06096.1 | RCCGE510_10335 | RCCGE510_06162 | precorrin-3B C17-methyltransferase; COG2073 Cobalamin biosynthesis protein CbiG. | COG1010 Precorrin-3B methylase. | 0.997 |
| EJT05622.1 | EJT06097.1 | RCCGE510_10335 | RCCGE510_06167 | precorrin-3B C17-methyltransferase; COG2073 Cobalamin biosynthesis protein CbiG. | COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family. | 0.951 |
| EJT05622.1 | EJT06099.1 | RCCGE510_10335 | RCCGE510_06177 | precorrin-3B C17-methyltransferase; COG2073 Cobalamin biosynthesis protein CbiG. | Putative precorrin-3b synthase; COG0155 Sulfite reductase, beta subunit (hemoprotein). | 0.647 |
| EJT05622.1 | EJT06100.1 | RCCGE510_10335 | RCCGE510_06182 | precorrin-3B C17-methyltransferase; COG2073 Cobalamin biosynthesis protein CbiG. | Precorrin 6A synthase; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | 0.951 |
| EJT05622.1 | cobH | RCCGE510_10335 | RCCGE510_06172 | precorrin-3B C17-methyltransferase; COG2073 Cobalamin biosynthesis protein CbiG. | precorrin-8X methylmutase; COG2082 Precorrin isomerase. | 0.975 |
| EJT05622.1 | cobQ | RCCGE510_10335 | RCCGE510_10390 | precorrin-3B C17-methyltransferase; COG2073 Cobalamin biosynthesis protein CbiG. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.742 |
| EJT05820.1 | EJT05622.1 | RCCGE510_07826 | RCCGE510_10335 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | precorrin-3B C17-methyltransferase; COG2073 Cobalamin biosynthesis protein CbiG. | 0.896 |
| EJT05820.1 | EJT06093.1 | RCCGE510_07826 | RCCGE510_06147 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | COG2875 Precorrin-4 methylase; Belongs to the precorrin methyltransferase family. | 0.896 |
| EJT05820.1 | EJT06094.1 | RCCGE510_07826 | RCCGE510_06152 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; COG2241 Precorrin-6B methylase 1. | 0.887 |
| EJT05820.1 | EJT06095.1 | RCCGE510_07826 | RCCGE510_06157 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | COG2099 Precorrin-6x reductase. | 0.869 |
| EJT05820.1 | EJT06096.1 | RCCGE510_07826 | RCCGE510_06162 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | COG1010 Precorrin-3B methylase. | 0.904 |
| EJT05820.1 | EJT06097.1 | RCCGE510_07826 | RCCGE510_06167 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family. | 0.889 |
| EJT05820.1 | EJT06099.1 | RCCGE510_07826 | RCCGE510_06177 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Putative precorrin-3b synthase; COG0155 Sulfite reductase, beta subunit (hemoprotein). | 0.974 |
| EJT05820.1 | EJT06100.1 | RCCGE510_07826 | RCCGE510_06182 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Precorrin 6A synthase; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | 0.869 |
| EJT05820.1 | cobH | RCCGE510_07826 | RCCGE510_06172 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | precorrin-8X methylmutase; COG2082 Precorrin isomerase. | 0.870 |
| EJT05820.1 | cobQ | RCCGE510_07826 | RCCGE510_10390 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.632 |