| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EJT04821.1 | EJT04822.1 | RCCGE510_12905 | RCCGE510_12910 | N-acetyltransferase GCN5. | COG0642 Signal transduction histidine kinase. | 0.517 |
| EJT04821.1 | EJT04823.1 | RCCGE510_12905 | RCCGE510_12915 | N-acetyltransferase GCN5. | Two-component response regulator protein; COG0784 FOG: CheY-like receiver. | 0.504 |
| EJT04821.1 | hisF | RCCGE510_12905 | RCCGE510_17606 | N-acetyltransferase GCN5. | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.406 |
| EJT04821.1 | hisH | RCCGE510_12905 | RCCGE510_17586 | N-acetyltransferase GCN5. | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.407 |
| EJT04821.1 | metH | RCCGE510_12905 | RCCGE510_11434 | N-acetyltransferase GCN5. | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.723 |
| EJT04822.1 | EJT04821.1 | RCCGE510_12910 | RCCGE510_12905 | COG0642 Signal transduction histidine kinase. | N-acetyltransferase GCN5. | 0.517 |
| EJT04822.1 | EJT04823.1 | RCCGE510_12910 | RCCGE510_12915 | COG0642 Signal transduction histidine kinase. | Two-component response regulator protein; COG0784 FOG: CheY-like receiver. | 0.947 |
| EJT04823.1 | EJT04821.1 | RCCGE510_12915 | RCCGE510_12905 | Two-component response regulator protein; COG0784 FOG: CheY-like receiver. | N-acetyltransferase GCN5. | 0.504 |
| EJT04823.1 | EJT04822.1 | RCCGE510_12915 | RCCGE510_12910 | Two-component response regulator protein; COG0784 FOG: CheY-like receiver. | COG0642 Signal transduction histidine kinase. | 0.947 |
| hisF | EJT04821.1 | RCCGE510_17606 | RCCGE510_12905 | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | N-acetyltransferase GCN5. | 0.406 |
| hisF | hisH | RCCGE510_17606 | RCCGE510_17586 | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.999 |
| hisF | metH | RCCGE510_17606 | RCCGE510_11434 | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.410 |
| hisH | EJT04821.1 | RCCGE510_17586 | RCCGE510_12905 | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | N-acetyltransferase GCN5. | 0.407 |
| hisH | hisF | RCCGE510_17586 | RCCGE510_17606 | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.999 |
| metH | EJT04821.1 | RCCGE510_11434 | RCCGE510_12905 | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | N-acetyltransferase GCN5. | 0.723 |
| metH | hisF | RCCGE510_11434 | RCCGE510_17606 | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.410 |