LOC108931101 protein (Scleropages formosus) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

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LOC108931101

Acid-sensing ion channel 1-like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (562 aa)

Predicted Functional Partners:

Z043_104959

0.547

LOC108935568

0.453

nedd4l

0.453

nedd4

0.453

LOC108929074

0.453

Hecw1

0.453

LOC108938565

0.435

ENSSFOP00015036928

0.435

STOML3

0.435

LOC108922685

0.435

Your Current Organism:

Scleropages formosus

NCBI taxonomy Id: 113540
Other names: Asian arowana, Asian bonytongue, Osteoglossum formosum, S. formosus, golden arowana, golden dragon fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSFOP00015036928	LOC108931101	ENSSFOP00015036928	ENSSFOP00015010302	annotation not available	Acid-sensing ion channel 1-like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.435
Hecw1	LOC108931101	ENSSFOP00015076976	ENSSFOP00015010302	E3 ubiquitin-protein ligase HECW1-like.	Acid-sensing ion channel 1-like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.453
LOC108922685	LOC108931101	ENSSFOP00015060766	ENSSFOP00015010302	Erythrocyte band 7 integral membrane protein-like.	Acid-sensing ion channel 1-like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.435
LOC108929074	LOC108931101	ENSSFOP00015041759	ENSSFOP00015010302	E3 ubiquitin-protein ligase NEDD4-like.	Acid-sensing ion channel 1-like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.453
LOC108931101	ENSSFOP00015036928	ENSSFOP00015010302	ENSSFOP00015036928	Acid-sensing ion channel 1-like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	annotation not available	0.435
LOC108931101	Hecw1	ENSSFOP00015010302	ENSSFOP00015076976	Acid-sensing ion channel 1-like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	E3 ubiquitin-protein ligase HECW1-like.	0.453
LOC108931101	LOC108922685	ENSSFOP00015010302	ENSSFOP00015060766	Acid-sensing ion channel 1-like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	Erythrocyte band 7 integral membrane protein-like.	0.435
LOC108931101	LOC108929074	ENSSFOP00015010302	ENSSFOP00015041759	Acid-sensing ion channel 1-like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	E3 ubiquitin-protein ligase NEDD4-like.	0.453
LOC108931101	LOC108935568	ENSSFOP00015010302	ENSSFOP00015016031	Acid-sensing ion channel 1-like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	E3 ubiquitin-protein ligase HECW1-like.	0.453
LOC108931101	LOC108938565	ENSSFOP00015010302	ENSSFOP00015020012	Acid-sensing ion channel 1-like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	Stom protein-like.	0.435
LOC108931101	STOML3	ENSSFOP00015010302	ENSSFOP00015049069	Acid-sensing ion channel 1-like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	Erythrocyte band 7 integral membrane protein-like.	0.435
LOC108931101	Z043_104959	ENSSFOP00015010302	ENSSFOP00015079205	Acid-sensing ion channel 1-like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	Cyclin-G-associated kinase-like.	0.547
LOC108931101	nedd4	ENSSFOP00015010302	ENSSFOP00015037882	Acid-sensing ion channel 1-like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	E3 ubiquitin-protein ligase.	0.453
LOC108931101	nedd4l	ENSSFOP00015010302	ENSSFOP00015035019	Acid-sensing ion channel 1-like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	E3 ubiquitin-protein ligase NEDD4-like isoform X1.	0.453
LOC108935568	LOC108931101	ENSSFOP00015016031	ENSSFOP00015010302	E3 ubiquitin-protein ligase HECW1-like.	Acid-sensing ion channel 1-like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.453
LOC108938565	LOC108931101	ENSSFOP00015020012	ENSSFOP00015010302	Stom protein-like.	Acid-sensing ion channel 1-like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.435
STOML3	LOC108931101	ENSSFOP00015049069	ENSSFOP00015010302	Erythrocyte band 7 integral membrane protein-like.	Acid-sensing ion channel 1-like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.435
Z043_104959	LOC108931101	ENSSFOP00015079205	ENSSFOP00015010302	Cyclin-G-associated kinase-like.	Acid-sensing ion channel 1-like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.547
nedd4	LOC108931101	ENSSFOP00015037882	ENSSFOP00015010302	E3 ubiquitin-protein ligase.	Acid-sensing ion channel 1-like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.453
nedd4	nedd4l	ENSSFOP00015037882	ENSSFOP00015035019	E3 ubiquitin-protein ligase.	E3 ubiquitin-protein ligase NEDD4-like isoform X1.	0.902

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Network Stats

number of nodes:

11

number of edges:

15

average node degree:

2.73

avg. local clustering coefficient:

0.919

expected number of edges:

12

PPI enrichment p-value:

0.234

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006865

Amino acid transport

9 of 32

1.84

4.26

9.28e-13

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0015424

ABC-type amino acid transporter activity

4 of 6

2.21

2.64

5.98e-06

GO:0022857

Transmembrane transporter activity

11 of 341

0.9

1.0

9.46e-08

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0043190

ATP-binding cassette (ABC) transporter complex

5 of 32

1.58

2.01

6.21e-06

GO:0005886

Plasma membrane

11 of 508

0.72

0.7

1.44e-06

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3790

Amino acid ABC transporter, permease protein, 3-TM domain, and ABC-type amino acid transport system, ATPase component, HisP-type

11 of 15

2.25

8.31

3.46e-21

CL:3808

Ligand-gated channel activity, and Amino acid ABC transporter, permease protein, 3-TM domain

5 of 6

2.31

3.98

8.93e-09

CL:3792

Bacterial periplasmic substrate-binding proteins, and ABC-type amino acid transport system, ATPase component, HisP-type

3 of 5

2.17

2.0

0.00013

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02010

ABC transporters

11 of 175

1.19

1.82

1.37e-11

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005886

Plasma membrane

9 of 367

0.78

0.68

0.00018

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0813

Transport

5 of 140

0.94

0.55

0.0262

KW-1003

Cell membrane

5 of 147

0.92

0.54

0.0262

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00528

Binding-protein-dependent transport system inner membrane component

5 of 27

1.65

1.89

3.17e-05

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR043429

ABC transporter membrane protein permease protein ArtM/GltK/GlnP/TcyL/YhdX-like

5 of 7

2.24

3.21

3.53e-07

IPR010065

Amino acid ABC transporter, permease protein, 3-TM domain

5 of 7

2.24

3.21

3.53e-07

IPR030679

ABC-type amino acid transport system, ATPase component, HisP-type

4 of 4

2.39

2.81

4.02e-06

IPR035906

MetI-like superfamily

5 of 27

1.65

1.95

2.16e-05

IPR000515

ABC transporter type 1, transmembrane domain MetI-like

5 of 27

1.65

1.95

2.16e-05

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00062

Bacterial periplasmic substrate-binding proteins

2 of 6

1.91

0.88

0.0211

SM00382

ATPases associated with a variety of cellular activities

5 of 98

1.1

0.85

0.0029

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