Z043_119692 protein (Scleropages formosus) - STRING interaction network

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Predicted Interactions

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gene co-occurrence

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protein homology

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Score

Z043_119692

Leucine-rich glioma-inactivated protein 1-like. (609 aa)

Predicted Functional Partners:

Z043_120636

0.519

adam11

0.519

adam22

0.519

LOC108920630

0.504

ENSSFOP00015061706

0.504

LOC108927392

0.471

LOC108935624

0.446

LOC108928893

0.411

LOC108934958

0.402

Your Current Organism:

Scleropages formosus

NCBI taxonomy Id: 113540
Other names: Asian arowana, Asian bonytongue, Osteoglossum formosum, S. formosus, golden arowana, golden dragon fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSFOP00015061706	Z043_119692	ENSSFOP00015061706	ENSSFOP00015077633	ADAM metallopeptidase domain 23a.	Leucine-rich glioma-inactivated protein 1-like.	0.504
ENSSFOP00015061706	Z043_120636	ENSSFOP00015061706	ENSSFOP00015019043	ADAM metallopeptidase domain 23a.	Uncharacterized protein.	0.473
ENSSFOP00015061706	adam11	ENSSFOP00015061706	ENSSFOP00015036512	ADAM metallopeptidase domain 23a.	Uncharacterized protein.	0.473
ENSSFOP00015061706	adam22	ENSSFOP00015061706	ENSSFOP00015052235	ADAM metallopeptidase domain 23a.	Disintegrin and metalloproteinase domain-containing protein 22-like.	0.456
LOC108920630	Z043_119692	ENSSFOP00015018798	ENSSFOP00015077633	Disintegrin and metalloproteinase domain-containing protein 23-like.	Leucine-rich glioma-inactivated protein 1-like.	0.504
LOC108920630	Z043_120636	ENSSFOP00015018798	ENSSFOP00015019043	Disintegrin and metalloproteinase domain-containing protein 23-like.	Uncharacterized protein.	0.468
LOC108920630	adam11	ENSSFOP00015018798	ENSSFOP00015036512	Disintegrin and metalloproteinase domain-containing protein 23-like.	Uncharacterized protein.	0.469
LOC108920630	adam22	ENSSFOP00015018798	ENSSFOP00015052235	Disintegrin and metalloproteinase domain-containing protein 23-like.	Disintegrin and metalloproteinase domain-containing protein 22-like.	0.463
LOC108927392	LOC108934958	ENSSFOP00015039621	ENSSFOP00015018845	Neurexophilin; May be signaling molecules that resemble neuropeptides.	BMP/retinoic acid-inducible neural-specific protein 3-like.	0.491
LOC108927392	Z043_119692	ENSSFOP00015039621	ENSSFOP00015077633	Neurexophilin; May be signaling molecules that resemble neuropeptides.	Leucine-rich glioma-inactivated protein 1-like.	0.471
LOC108928893	LOC108934958	ENSSFOP00015061386	ENSSFOP00015018845	Neurexophilin; May be signaling molecules that resemble neuropeptides.	BMP/retinoic acid-inducible neural-specific protein 3-like.	0.493
LOC108928893	Z043_119692	ENSSFOP00015061386	ENSSFOP00015077633	Neurexophilin; May be signaling molecules that resemble neuropeptides.	Leucine-rich glioma-inactivated protein 1-like.	0.411
LOC108934958	LOC108927392	ENSSFOP00015018845	ENSSFOP00015039621	BMP/retinoic acid-inducible neural-specific protein 3-like.	Neurexophilin; May be signaling molecules that resemble neuropeptides.	0.491
LOC108934958	LOC108928893	ENSSFOP00015018845	ENSSFOP00015061386	BMP/retinoic acid-inducible neural-specific protein 3-like.	Neurexophilin; May be signaling molecules that resemble neuropeptides.	0.493
LOC108934958	LOC108935624	ENSSFOP00015018845	ENSSFOP00015054660	BMP/retinoic acid-inducible neural-specific protein 3-like.	Neurexophilin; May be signaling molecules that resemble neuropeptides.	0.476
LOC108934958	Z043_119692	ENSSFOP00015018845	ENSSFOP00015077633	BMP/retinoic acid-inducible neural-specific protein 3-like.	Leucine-rich glioma-inactivated protein 1-like.	0.402
LOC108935624	LOC108934958	ENSSFOP00015054660	ENSSFOP00015018845	Neurexophilin; May be signaling molecules that resemble neuropeptides.	BMP/retinoic acid-inducible neural-specific protein 3-like.	0.476
LOC108935624	Z043_119692	ENSSFOP00015054660	ENSSFOP00015077633	Neurexophilin; May be signaling molecules that resemble neuropeptides.	Leucine-rich glioma-inactivated protein 1-like.	0.446
Z043_119692	ENSSFOP00015061706	ENSSFOP00015077633	ENSSFOP00015061706	Leucine-rich glioma-inactivated protein 1-like.	ADAM metallopeptidase domain 23a.	0.504
Z043_119692	LOC108920630	ENSSFOP00015077633	ENSSFOP00015018798	Leucine-rich glioma-inactivated protein 1-like.	Disintegrin and metalloproteinase domain-containing protein 23-like.	0.504

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Network Stats

number of nodes:

11

number of edges:

49

average node degree:

8.91

avg. local clustering coefficient:

0.908

expected number of edges:

11

PPI enrichment p-value:

1.11e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000270

Peptidoglycan metabolic process

8 of 28

1.88

3.99

4.19e-11

GO:0009252

Peptidoglycan biosynthetic process

7 of 22

1.92

3.87

3.13e-10

GO:0071554

Cell wall organization or biogenesis

8 of 33

1.81

3.78

4.19e-11

GO:0008360

Regulation of cell shape

7 of 24

1.89

3.76

3.40e-10

GO:0071555

Cell wall organization

6 of 25

1.8

3.04

2.50e-08

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016881

Acid-amino acid ligase activity

3 of 9

1.94

1.19

0.0049

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3311

Mixed, incl. Regulation of cell shape, and Cell cycle

11 of 43

1.83

5.15

1.93e-17

CL:3312

Mixed, incl. Regulation of cell shape, and Peptidoglycan muralytic activity

10 of 38

1.84

4.92

7.55e-16

CL:3376

Mixed, incl. Cell cycle protein, and Serine-type exopeptidase activity

4 of 5

2.32

3.15

6.65e-07

CL:3360

Regulation of cell shape, and Peptidoglycan muralytic activity

5 of 14

1.97

3.07

1.58e-07

CL:3317

Mur ligase, central, and Glycosylation

4 of 6

2.24

3.01

1.03e-06

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00550

Peptidoglycan biosynthesis

6 of 25

1.8

2.97

4.46e-08

map00471

D-Glutamine and D-glutamate metabolism

2 of 4

2.12

1.04

0.0110

map01502

Vancomycin resistance

2 of 7

1.88

0.91

0.0175

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0961

Cell wall biogenesis/degradation

6 of 15

2.02

3.67

5.59e-09

KW-0132

Cell division

6 of 22

1.86

3.19

1.92e-08

KW-0131

Cell cycle

6 of 22

1.86

3.19

1.92e-08

KW-0573

Peptidoglycan synthesis

5 of 13

2.01

3.17

1.07e-07

KW-0436

Ligase

3 of 60

1.12

0.56

0.0449

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF08245

Mur ligase middle domain

3 of 5

2.2

1.58

0.00097

PF03717

Penicillin-binding Protein dimerisation domain

2 of 2

2.42

0.97

0.0169

PF02875

Mur ligase family, glutamate ligase domain

2 of 3

2.24

0.93

0.0187

PF01225

Mur ligase family, catalytic domain

2 of 3

2.24

0.93

0.0187

PF00905

Penicillin binding protein transpeptidase domain

2 of 4

2.12

0.92

0.0187

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR013221

Mur ligase, central

3 of 4

2.3

1.48

0.0017

IPR036615

Mur ligase, C-terminal domain superfamily

3 of 5

2.2

1.46

0.0017

IPR036565

Mur-like, catalytic domain superfamily

3 of 5

2.2

1.46

0.0017

IPR036138

Penicillin-binding protein, dimerisation domain superfamily

2 of 2

2.42

0.89

0.0232

IPR005311

Penicillin-binding protein, dimerisation domain

2 of 2

2.42

0.89

0.0232

(more ...)

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