STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDT75407.12-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase. (174 aa)    
Predicted Functional Partners:
SDT75398.1
Dihydropteroate synthase.
 
 
 0.999
SDT75404.1
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 0.999
SDT39169.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 
 0.998
folE
GTP cyclohydrolase I.
 
  
 0.992
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
 
 
 0.924
SDT60616.1
Phenazine biosynthesis protein phzE.
  
 
 0.890
SDT75410.1
Protein of unknown function.
       0.889
SDT67908.1
Dihydrofolate synthase / folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.
 
 
 0.861
SDT75401.1
Hypothetical protein.
       0.773
SDS91841.1
Para-aminobenzoate synthetase component 1; Manually curated.
 
 
 0.728
Your Current Organism:
Actinoplanes derwentensis
NCBI taxonomy Id: 113562
Other names: A. derwentensis, ATCC 49798, DSM 43941, IFO 14935, JCM 7556, NBRC 14935, NCIB 12875, NCIB:12875, NCIMB 12875, NRRL B-16692, strain LA 107
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