STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDT75752.1Nickel uptake regulator, Fur family; Manually curated; Belongs to the Fur family. (140 aa)    
Predicted Functional Partners:
SDT62949.1
Glutamate synthase (NADH) large subunit.
    
 0.910
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.882
SDT75760.1
Uncharacterized conserved protein, DUF849 family.
 
     0.879
SDT75756.1
Hypothetical protein; Belongs to the GcvT family.
       0.872
SDT75762.1
L-asparaginase II.
       0.794
SDT75748.1
4-amino-4-deoxychorismate lyase.
       0.709
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.689
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.687
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
   0.681
SDT68664.1
RNA polymerase sigma factor, sigma-70 family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
 
 0.613
Your Current Organism:
Actinoplanes derwentensis
NCBI taxonomy Id: 113562
Other names: A. derwentensis, ATCC 49798, DSM 43941, IFO 14935, JCM 7556, NBRC 14935, NCIB 12875, NCIB:12875, NCIMB 12875, NRRL B-16692, strain LA 107
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.