STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDT80010.1Calcineurin-like phosphoesterase. (261 aa)    
Predicted Functional Partners:
SDT78200.1
Exonuclease SbcC.
  
 0.997
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.991
SDS31669.1
5'-3' exonuclease.
   
 0.972
SDT76826.1
ATP-dependent DNA helicase, Rep family.
  
 0.969
SDT64538.1
Menaquinol-cytochrome c reductase cytochrome b subunit precursor.
    
 
 0.905
SDT40395.1
ATP-dependent DNA helicase RecQ.
   
 0.889
SDT71646.1
ATP-dependent DNA helicase, RecQ-like.
   
 0.889
SDT79410.1
ATP-dependent DNA helicase RecQ.
   
 0.889
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 0.871
SDT75729.1
ATP-dependent DNA helicase DinG.
   
 0.865
Your Current Organism:
Actinoplanes derwentensis
NCBI taxonomy Id: 113562
Other names: A. derwentensis, ATCC 49798, DSM 43941, IFO 14935, JCM 7556, NBRC 14935, NCIB 12875, NCIB:12875, NCIMB 12875, NRRL B-16692, strain LA 107
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.