STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CEJ87940.1Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function. (272 aa)    
Predicted Functional Partners:
CEJ87939.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
       0.693
CEJ84859.1
Integral membrane sensor hybrid histidine kinase.
   
 0.579
CEJ87941.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
       0.543
CEJ87937.1
Cation efflux protein.
       0.481
CEJ85411.1
Histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
 0.470
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.419
parE
DNA topoisomerase IV, subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
    
 
 0.419
Your Current Organism:
Hyphomicrobium sp. GJ21
NCBI taxonomy Id: 113574
Other names: H. sp. GJ21
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