STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tiaSPutative DNA-binding protein containing a Zn-ribbon domain; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. (423 aa)    
Predicted Functional Partners:
GAH_01054
Uncharacterized protein conserved in archaea.
 
     0.788
mfnA
Tyrosine decarboxylase MnfA; Catalyzes the decarboxylation of L-aspartate to produce beta- alanine; Belongs to the group II decarboxylase family. MfnA subfamily.
      
 0.727
GAH_01694
Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit.
  
     0.719
hjc
Holliday junction resolvase - archaeal type; A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products; Belongs to the Holliday junction resolvase Hjc family.
       0.671
ribK
Transcriptional regulator of a riboflavin/FAD biosynthetic operon; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
  
     0.669
GAH_00164
Nicotinamide-nucleotide adenylyltransferase.
  
     0.658
GAH_01044
DNA-directed RNA polymerase, subunit B''; Belongs to the RNA polymerase beta chain family.
 
   
 0.640
GAH_02047
Uncharacterized protein conserved in archaea; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family.
  
     0.638
GAH_00540
Putative archaeal kinase {sugar kinase superfamily}.
 
     0.605
GAH_00868
Putative nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module.
 
     0.599
Your Current Organism:
Geoglobus ahangari
NCBI taxonomy Id: 113653
Other names: ATCC BAA-425, G. ahangari, Geoglobus ahangari Kashefi et al. 2002, hyperthermophile str. 234, strain 234
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