STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spt4DNA-directed RNA polymerase, subunit E'; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. (62 aa)    
Predicted Functional Partners:
GAH_01871
DNA-directed RNA polymerase {rpoE} and eukaryotic form.
 
 
 0.995
spt5
Ribosomal protein L24p/L26e; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
  
 
 0.976
rps27ae
Ribosomal protein S27AE; Belongs to the eukaryotic ribosomal protein eS31 family.
  
    0.976
GAH_01873
Uncharacterized protein conserved in archaea; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
 
    0.900
kae1
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
       0.895
rps24e
Ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family.
 
    0.882
GAH_01877
Kae1-associated kinase Bud32.
 
     0.881
GAH_01042
DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.747
GAH_00609
DNA-directed RNA polymerase, subunit RPC10 {contains C4-type Zn-finger}.
   
  
 0.690
rps6e
Ribosomal protein S6E {S10}; Belongs to the eukaryotic ribosomal protein eS6 family.
 
    0.677
Your Current Organism:
Geoglobus ahangari
NCBI taxonomy Id: 113653
Other names: ATCC BAA-425, G. ahangari, Geoglobus ahangari Kashefi et al. 2002, hyperthermophile str. 234, strain 234
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