node1 | node2 | node1 annotation | node2 annotation | score |
A0A067NF65 | A0A067NFS9 | Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. | Guanylate kinase-like domain-containing protein. | 0.698 |
A0A067NF65 | A0A067NG73 | Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. | MGS domain-containing protein. | 0.678 |
A0A067NF65 | A0A067NNI7 | Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. | A_deaminase domain-containing protein. | 0.689 |
A0A067NF65 | A0A067NRX8 | Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.710 |
A0A067NF65 | A0A067NYA6 | Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. | Uncharacterized protein. | 0.795 |
A0A067NF65 | A0A067NYH1 | Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. | GRIP domain-containing protein. | 0.650 |
A0A067NF65 | A0A067NYI3 | Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.741 |
A0A067NF65 | A0A067P034 | Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. | Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | 0.711 |
A0A067NFS9 | A0A067NF65 | Guanylate kinase-like domain-containing protein. | Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. | 0.698 |
A0A067NFS9 | A0A067NJD6 | Guanylate kinase-like domain-containing protein. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.935 |
A0A067NFS9 | A0A067NMQ2 | Guanylate kinase-like domain-containing protein. | Diphthami_syn_2 domain-containing protein. | 0.815 |
A0A067NFS9 | A0A067NRX8 | Guanylate kinase-like domain-containing protein. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.954 |
A0A067NFS9 | A0A067NYA6 | Guanylate kinase-like domain-containing protein. | Uncharacterized protein. | 0.729 |
A0A067NFS9 | A0A067NYH1 | Guanylate kinase-like domain-containing protein. | GRIP domain-containing protein. | 0.905 |
A0A067NFS9 | A0A067NYI3 | Guanylate kinase-like domain-containing protein. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.491 |
A0A067NFS9 | A0A067P034 | Guanylate kinase-like domain-containing protein. | Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | 0.894 |
A0A067NG73 | A0A067NF65 | MGS domain-containing protein. | Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. | 0.678 |
A0A067NG73 | A0A067NNI7 | MGS domain-containing protein. | A_deaminase domain-containing protein. | 0.918 |
A0A067NG73 | A0A067NRX8 | MGS domain-containing protein. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.935 |
A0A067NG73 | A0A067NYA6 | MGS domain-containing protein. | Uncharacterized protein. | 0.665 |