STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A067P2B9Uncharacterized protein. (1259 aa)    
Predicted Functional Partners:
A0A067NTL6
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
   
 0.959
A0A067NMD7
DUF1767 domain-containing protein.
    
 0.943
A0A067NM43
Uncharacterized protein.
    
 0.933
A0A067P2E3
ERCC4 domain-containing protein.
    
 0.926
A0A067NLG6
Uncharacterized protein.
    
 
 0.920
A0A067NP91
Ribosomal protein; Belongs to the universal ribosomal protein uL1 family.
    
 0.910
A0A067NQX1
MPN domain-containing protein.
    
 0.902
A0A067P1C0
NTF2 domain-containing protein.
    
 0.898
A0A067NFP3
Uncharacterized protein.
    
 0.881
A0A067NZ97
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.881
Your Current Organism:
Pleurotus ostreatus
NCBI taxonomy Id: 1137138
Other names: P. ostreatus PC15, Pleurotus ostreatus PC15
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.